Evidence map›Paper›PMID 34987638›Full record

ArticleTheranostics2022

An MMP-degradable and conductive hydrogel to stabilize HIF-1α for recovering cardiac functions.

Xiaojuan Wei, Si Chen, Tian Xie, Hongchi Chen, Xin Jin, Jumin Yang, Shafaq Sahar, Huanlei Huang, Shuoji Zhu, Nanbo Liu and 4 more

Open access · goldAbstract read
In one paragraph

Article in Theranostics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed
6.3field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 45 citations in OpenAlex.

  1. Review
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  10. [Advances in hydrogel drug delivery systems for myocardial infarction treatment].Zhejiang da xue xue bao. Yi xue ban = Journal of Zhejiang University. Medical sciences · 2025
    Review
  11. Review
  12. Article
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  14. Review
  15. Article
  16. Review
  17. Review
  18. Smart Hydrogels for Tissue Regeneration.Macromolecular bioscience · 2024
    Review
  19. Biofabrication of engineered blood vessels for biomedical applications.Science and technology of advanced materials · 2024
    Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 7 institutions in 1 country.

Xiaojuan WeiInstitute of Microsurgery on Extremities, Shanghai Jiao Tong University Affiliated Shanghai Sixth People's Hospital, Shanghai 200233, China.
Si ChenCollege of Chemical and Biological Engineering, Zhejiang University, Hangzhou 310027, China.
Tian XieSchool of Materials Science and Engineering, Tianjin Key Laboratory of Composite and Functional Materials, Tianjin University, Tianjin 300350, China.
Hongchi ChenDepartment of Orthopedic Surgery, Shanghai Jiao Tong University Affiliated Shanghai Sixth People's Hospital, Shanghai 200233, China.
Xin JinSchool of Materials Science and Engineering, Tianjin Key Laboratory of Composite and Functional Materials, Tianjin University, Tianjin 300350, China.
Jumin YangSchool of Materials Science and Engineering, Tianjin Key Laboratory of Composite and Functional Materials, Tianjin University, Tianjin 300350, China.
Shafaq SaharCollege of Chemical and Biological Engineering, Zhejiang University, Hangzhou 310027, China.
Huanlei HuangGuangdong Cardiovascular Institute, Guangdong Provincial People's Hospital, Guangdong Academy of Medical Sciences, Guangzhou, Guangdong 510100, China.
Shuoji ZhuGuangdong Cardiovascular Institute, Guangdong Provincial People's Hospital, Guangdong Academy of Medical Sciences, Guangzhou, Guangdong 510100, China.
Nanbo LiuGuangdong Cardiovascular Institute, Guangdong Provincial People's Hospital, Guangdong Academy of Medical Sciences, Guangzhou, Guangdong 510100, China.
Changjiang YuGuangdong Cardiovascular Institute, Guangdong Provincial People's Hospital, Guangdong Academy of Medical Sciences, Guangzhou, Guangdong 510100, China.
Ping ZhuGuangdong Cardiovascular Institute, Guangdong Provincial People's Hospital, Guangdong Academy of Medical Sciences, Guangzhou, Guangdong 510100, China.
Wei WangCollege of Chemical and Biological Engineering, Zhejiang University, Hangzhou 310027, China.
Wei ZhangInstitute of Microsurgery on Extremities, Shanghai Jiao Tong University Affiliated Shanghai Sixth People's Hospital, Shanghai 200233, China.
Guangdong Academy of Medical Sciences · CNTianjin University · CNGuangdong Provincial People's Hospital · CNShanghai Jiao Tong University · CNShanghai Sixth People's Hospital · CNZhejiang University · CNZhejiang University of Science and Technology · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AnimalsCell LineFibroblastsHydrogelsHypoxia-Inducible Factor 1, alpha SubunitMatrix MetalloproteinasesMiceMyocardial InfarctionRatsRats, Sprague-DawleyHIF1A protein, humanHydrogelsHypoxia-Inducible Factor 1, alpha SubunitMatrix Metalloproteinasesconductivityhypoxia-inducible factor-1αinjectable hydrogelmatrix metalloproteinasemyocardial infarction

Identifiers

PMID34987638
PMCPMC8690911
OpenAlexW3211672251

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.