Evidence map›Paper›PMID 34987496›Full record

ArticleFrontiers in immunology2021

IFNγ and iNOS-Mediated Alterations in the Bone Marrow and Thymus and Its Impact on

Palmira Barreira-Silva, Rita Melo-Miranda, Claudia Nobrega, Susana Roque, Cláudia Serre-Miranda, Margarida Borges, Gisela Armada, Daniela de Sá Calçada, Samuel M Behar, Rui Appelberg and 1 more

Open access · goldAbstract readComparative Study
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in immunology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.3field-weighted citation impact, top 45% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 5 institutions in 3 countries.

Palmira Barreira-SilvaLife and Health Sciences Research Institute (ICVS), School of Medicine, University of Minho, Braga, Portugal.
Rita Melo-MirandaLife and Health Sciences Research Institute (ICVS), School of Medicine, University of Minho, Braga, Portugal.
Claudia NobregaLife and Health Sciences Research Institute (ICVS), School of Medicine, University of Minho, Braga, Portugal.
Susana RoqueLife and Health Sciences Research Institute (ICVS), School of Medicine, University of Minho, Braga, Portugal.
Cláudia Serre-MirandaLife and Health Sciences Research Institute (ICVS), School of Medicine, University of Minho, Braga, Portugal.
Margarida BorgesResearch Unit on Applied Molecular Biosciences (UCIBIO)/Rede de Química e Tecnologia (REQUINTE), Departamento de Ciências Biológicas, Faculdade de Farmácia, Universidade do Porto, Porto, Portugal.
Gisela ArmadaLife and Health Sciences Research Institute (ICVS), School of Medicine, University of Minho, Braga, Portugal.
Daniela de Sá CalçadaLife and Health Sciences Research Institute (ICVS), School of Medicine, University of Minho, Braga, Portugal.
Samuel M BeharDepartment of Microbiology and Physiological Systems, University of Massachusetts Medical School, Worcester, MA, United States.
Rui AppelbergInstituto de Investigação e Inovação em Saúde (i3S), Instituto de Investigação e Inovação em Saúde, Universidade do Porto, Porto, Portugal.
Margarida Correia-NevesLife and Health Sciences Research Institute (ICVS), School of Medicine, University of Minho, Braga, Portugal.
University of Minho · PTi3S - Instituto de Investigação e Inovação em Saúde, Universidade do Porto · PTKarolinska Institutet · SERede de Química e Tecnologia · PTUniversity of Massachusetts Chan Medical School · US

Funding

Regulation of CD8+ T cell immunity to tuberculosis (pending title)R01AI106725 · NIAID · UNIV OF MASSACHUSETTS MED SCH WORCESTER · PI BEHAR, SAMUEL M · 2013 to 2022
$6.1M
NIAID NIH HHS R01 AI106725
6 · The paper itself

Abstract

Disseminated infection with the high virulence strain of

Indexed as

AnimalsApoptosisAtrophyBone MarrowBone Marrow TransplantationCell DifferentiationDNA-Binding ProteinsFemaleInterferon-gammaLymphoid Progenitor CellsMiceMice, Inbred C57BLMice, KnockoutMice, TransgenicMycobacterium aviumNitric OxideDNA-Binding ProteinsInterferon-gammaNitric OxideNitric Oxide Synthase Type IINos2 protein, mouseRag2 protein, mouseBM T cell precursorsIFN gammaMycobacterium avium infectionnitric oxidethymocyte differentiationthymus premature atrophy

Identifiers

PMID34987496
PMCPMC8721011
OpenAlexW4200252202

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.