Evidence map›Paper›PMID 34987383›Full record

ReviewFrontiers in pharmacology2021

The Roles of Cardiovascular H

Joachim Neumann, Uwe Kirchhefer, Stefan Dhein, Britt Hofmann, Ulrich Gergs

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in pharmacology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
2.1field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 35 citations in OpenAlex.

  1. Use of Antihistamine Drugs in Colitis: A Review.Pharmaceuticals (Basel, Switzerland) · 2026
    Review
  2. Observational
  3. Mirtazapine is a functional antagonist at cardiac human HNaunyn-Schmiedeberg's archives of pharmacology · 2026
    Article
  4. Article
  5. Article
  6. The use of antihistamine and antihistamine-like drugs for cancer-related pain: a narrative review.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2025
    Review
  7. Contractile effects of dexmedetomidine in the human heart.Naunyn-Schmiedeberg's archives of pharmacology · 2025
    Article
  8. Article
  9. Effects of Psilocin and Psilocybin on Human 5-HTPharmaceuticals (Basel, Switzerland) · 2025
    Article
  10. Stimulation of histamine HNaunyn-Schmiedeberg's archives of pharmacology · 2025
    Article
  11. Clozapine is a functional antagonist at cardiac human HNaunyn-Schmiedeberg's archives of pharmacology · 2025
    Article
  12. Article
  13. Mast Cells in Cardiac Remodeling: Focus on the Right Ventricle.Journal of cardiovascular development and disease · 2024
    Review
  14. Review
  15. Clonidine stimulates force of contraction via histamine HNaunyn-Schmiedeberg's archives of pharmacology · 2024
    Article
  16. Lysergic acid diethylamide stimulates cardiac human HNaunyn-Schmiedeberg's archives of pharmacology · 2024
    Article
  17. Ergometrine stimulates histamine HNaunyn-Schmiedeberg's archives of pharmacology · 2023
    Article
  18. Glucagon and Its Receptors in the Mammalian Heart.International journal of molecular sciences · 2023
    Review
  19. Mast Cells and Basophils in IgE-Independent Anaphylaxis.International journal of molecular sciences · 2023
    Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Joachim NeumannInstitut für Pharmakologie und Toxikologie, Medizinische Fakultät, Martin-Luther-Universität Halle-Wittenberg, Halle, Germany.
Uwe KirchheferInstitut für Pharmakologie und Toxikologie, Westfälische Wilhelms-Universität, Münster, Germany.
Stefan DheinLandratsamt Altenburger Land, Altenburg, Germany.
Britt HofmannHerzchirurgie, Medizinische Fakultät, Martin-Luther-Universität Halle-Wittenberg, Halle, Germany.
Ulrich GergsInstitut für Pharmakologie und Toxikologie, Medizinische Fakultät, Martin-Luther-Universität Halle-Wittenberg, Halle, Germany.
Martin Luther University Halle-Wittenberg · DEKlinikum Altenburger Land · DEUniversity of Münster · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This review addresses pharmacological, structural and functional relationships among H

Indexed as

arrhythmiascontractil effectH2 histamine receptorheart failureischemia - reperfusion

Identifiers

PMID34987383
PMCPMC8720924
OpenAlexW4200055433

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.