Evidence map›Paper›PMID 34987367›Full record

ArticleFrontiers in human neuroscience2021

Delirium, Caffeine, and Perioperative Cortical Dynamics.

Hyoungkyu Kim, Amy McKinney, Joseph Brooks, George A Mashour, UnCheol Lee, Phillip E Vlisides

2 registry-linked trialsOpen access · goldAbstract read
In one paragraph

Article in Frontiers in human neuroscience, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.0field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05574400 phase2completednot on this mapstarted 2023, after this paper: background citation

The Caffeine, Postoperative Delirium, and Change in Outcomes After Surgery (CAPACHINOS-2) Study

TypeinterventionalSponsorUniversity of MichiganRan2023 to 2026Enrolled250ConditionsPostoperative Delirium, Postoperative Cognitive Dysfunction, Mild Cognitive ImpairmentArmsDextrose Water, Caffeine citrate
NCT07536854 completednot on this mapstarted 2024, after this paper: background citation

Longitudinal Frontal EEG Trajectories Reveal Divergent Cortical Dynamics in Delirium After Severe Trauma

Typeobservational_patient_registrySponsorAjou University School of MedicineRan2024 to 2025Enrolled73ConditionsDelirium, Trauma, Brain Dysfunction, Critical Illness
3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 9 citations in OpenAlex.

  1. Trial
  2. Review
  3. Article
  4. Article
  5. Delirium and Cortical Complexity.The journals of gerontology. Series A, Biological sciences and medical sciences · 2022
    Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Hyoungkyu KimDepartment of Anesthesiology, University of Michigan Medical School, Ann Arbor, MI, United States.
Amy McKinneyDepartment of Anesthesiology, University of Michigan Medical School, Ann Arbor, MI, United States.
Joseph BrooksDepartment of Anesthesiology, University of Michigan Medical School, Ann Arbor, MI, United States.
George A MashourDepartment of Anesthesiology, University of Michigan Medical School, Ann Arbor, MI, United States.
UnCheol LeeDepartment of Anesthesiology, University of Michigan Medical School, Ann Arbor, MI, United States.
Phillip E VlisidesDepartment of Anesthesiology, University of Michigan Medical School, Ann Arbor, MI, United States.
University of Michigan–Ann Arbor · US

Funding

Michigan Institute for Clinical and Health Research (MICHR)UL1TR002240 · NCATS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI LUMENG, JULIE C, MASHOUR, GEORGE ALEXANDER · 2017 to 2022
$54.9M
Neurocognitive Recovery following Surgery and General AnesthesiaK23GM126317 · NIGMS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI VLISIDES, PHILLIP ELEAS · 2018 to 2021
$764k
NCATS NIH HHS UL1 TR002240NIGMS NIH HHS K23 GM126317
6 · The paper itself

Abstract

Delirium is a major public health issue associated with considerable morbidity and mortality, particularly after surgery. While the neurobiology of delirium remains incompletely understood, emerging evidence suggests that cognition requires close proximity to a system state called

Indexed as

cognitive agingcognitive dysfunctiondeliriumelectroencephalographypostoperative cognitive changes

Identifiers

PMID34987367
PMCPMC8722672
OpenAlexW4200493456

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.