Evidence map›Paper›PMID 34987295›Full record

ArticleAnnals of gastroenterology

Surgical versus non-operative initial management of post-endoscopic retrograde cholangiopancreatography perforation: a systematic review and meta-analysis.

Athina A Samara, Alexandros Diamantis, Konstantinos Perivoliotis, Georgios Mavrovounis, Dimitrios Symeonidis, Ioannis Baloyiannis, Dimitris Zacharoulis

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In one paragraph

Article in Annals of gastroenterology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Endoscopic retrograde cholangiopancreatography-related duodenal perforations: A systematic review and meta-analysis of management and outcomes.Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology · 2025
    Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Athina A SamaraDepartment of Surgery, University Hospital of Larissa, Greece.
Alexandros DiamantisDepartment of Surgery, University Hospital of Larissa, Greece.
Konstantinos PerivoliotisDepartment of Surgery, University Hospital of Larissa, Greece.
Georgios MavrovounisDepartment of Surgery, University Hospital of Larissa, Greece.
Dimitrios SymeonidisDepartment of Surgery, University Hospital of Larissa, Greece.
Ioannis BaloyiannisDepartment of Surgery, University Hospital of Larissa, Greece.
Dimitris ZacharoulisDepartment of Surgery, University Hospital of Larissa, Greece.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundIn the present study we performed a systematic review and meta-analysis regarding the initial management of perforations following endoscopic retrograde cholangiopancreatography (ERCP).

methodA systematic review and meta-analysis was conducted according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines and the Cochrane Handbook for Systematic Reviews of Interventions.

resultIn total, 10 comparative studies and 223 patients with post-ERCP perforations were included in the present study. In type I and II perforations, the success rate of initial surgical management was higher compared to the non-operative management (NOM) group (P=0.09 and P=0.02, respectively). There was no statistically significant difference in mortality rates or length of hospital stay between initial surgical and NOM management for any type of perforation.

conclusionsThe current meta-analysis demonstrated the significance of the initial management of patients with post-ERCP perforations. Whether a surgical or an endoscopic approach is chosen, the patient should immediately be evaluated by an experienced surgeon or endoscopist.

Indexed as

complicationsduodenal perforationEndoscopic retrograde cholangiopancreatographyiatrogenic duodenal injurysurgical management

Identifiers

PMID34987295
PMCPMC8713336

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.