Evidence map›Paper›PMID 34987291›Full record

ArticleAnnals of gastroenterology

Retrospective analysis of the outcomes of endoscopic submucosal dissection for the diagnosis and treatment of subepithelial lesions in a center with high expertise.

João Santos-Antunes, Margarida Marques, Rui Morais, Francisco Baldaque-Silva, Filipe Vilas-Boas, Pedro Moutinho-Ribeiro, Susana Lopes, Fátima Carneiro, Guilherme Macedo

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Article in Annals of gastroenterology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

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4 · The record

Corrections and comments

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5 · Who and what money

Authors and funding

9 authors.

João Santos-AntunesGastroenterology Department, Faculty of Medicine, Centro Hospitalar S. João, Porto, Portugal (João Santos-Antunes, Margarida Marques, Rui Morais, Filipe Vilas-Boas, Pedro Moutinho-Ribeiro, Susana Lopes, Guilherme Macedo).
Margarida MarquesGastroenterology Department, Faculty of Medicine, Centro Hospitalar S. João, Porto, Portugal (João Santos-Antunes, Margarida Marques, Rui Morais, Filipe Vilas-Boas, Pedro Moutinho-Ribeiro, Susana Lopes, Guilherme Macedo).
Rui MoraisGastroenterology Department, Faculty of Medicine, Centro Hospitalar S. João, Porto, Portugal (João Santos-Antunes, Margarida Marques, Rui Morais, Filipe Vilas-Boas, Pedro Moutinho-Ribeiro, Susana Lopes, Guilherme Macedo).
Francisco Baldaque-SilvaDivision of Medicine, Department of Upper Gastrointestinal Diseases, Karolinska University Hospital and Karolinska Institute, Stockholm, Sweden (Francisco Baldaque-Silva).
Filipe Vilas-BoasGastroenterology Department, Faculty of Medicine, Centro Hospitalar S. João, Porto, Portugal (João Santos-Antunes, Margarida Marques, Rui Morais, Filipe Vilas-Boas, Pedro Moutinho-Ribeiro, Susana Lopes, Guilherme Macedo).
Pedro Moutinho-RibeiroGastroenterology Department, Faculty of Medicine, Centro Hospitalar S. João, Porto, Portugal (João Santos-Antunes, Margarida Marques, Rui Morais, Filipe Vilas-Boas, Pedro Moutinho-Ribeiro, Susana Lopes, Guilherme Macedo).
Susana LopesGastroenterology Department, Faculty of Medicine, Centro Hospitalar S. João, Porto, Portugal (João Santos-Antunes, Margarida Marques, Rui Morais, Filipe Vilas-Boas, Pedro Moutinho-Ribeiro, Susana Lopes, Guilherme Macedo).
Fátima CarneiroPathology Department, Faculty of Medicine, Centro Hospitalar S. João, Porto, Portugal (Fátima Carneiro).
Guilherme MacedoGastroenterology Department, Faculty of Medicine, Centro Hospitalar S. João, Porto, Portugal (João Santos-Antunes, Margarida Marques, Rui Morais, Filipe Vilas-Boas, Pedro Moutinho-Ribeiro, Susana Lopes, Guilherme Macedo).

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundUse of endoscopic submucosal dissection (ESD) for the diagnosis and treatment of subepithelial lesions (SELs) is limited in the West, and the best approach for these lesions is still debated. In this study we describe our experience regarding the usefulness, safety and outcomes of ESD for SELs.

methodWe performed a retrospective analysis of ESD in the diagnosis and treatment of SELs between November 2010 and February 2021.

resultsA total of 634 ESDs were reviewed. Fifty-five (9%) were performed in SELs, 6 in the esophagus, 34 in the stomach, and 15 in the rectum. ESD was technically successful in 53 lesions (96%). Most of them (82%) had previous endoscopic ultrasound evaluation, but only 20% had a histological diagnosis previous to the ESD. Neuroendocrine tumors, gastrointestinal stromal tumors, and granular cell tumors accounted for 38% of the procedures, with a 100% rate of

conclusionOur real-life experience showed that ESD can be an effective and safe diagnostic tool for undetermined SELs, as well as an effective treatment for neoplastic SELs with malignant potential.

Indexed as

Endoscopic submucosal dissectionendoscopic ultrasoundreal-life experiencesubepithelial lesionswestern series

Identifiers

PMID34987291
PMCPMC8713347

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.