Evidence map›Paper›PMID 34987258›Full record

ArticleThe Canadian journal of hospital pharmacy2022

Patterns of Antimicrobial Use in an Outpatient Hemodialysis Unit.

Sylvia Sivarajahkumar, Miranda So, Andrew M Morris, Charmaine Lok, Chaim M Bell, Marisa Battistella

Open access · bronzeAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in The Canadian journal of hospital pharmacy, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.6field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Review
  2. Intermittent hemodialysis: a review of the top antimicrobial stewardship practices to be employed.Antimicrobial stewardship & healthcare epidemiology : ASHE · 2024
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Sylvia Sivarajahkumar, HBSc, BScPhm, is with the University Health Network and the Leslie Dan Faculty of Pharmacy, University of Toronto, Toronto, Ontario.
Miranda So, BScPhm, PharmD, is with the University Health Network and the Leslie Dan Faculty of Pharmacy, University of Toronto, Toronto, Ontario.
Andrew M Morris, MD, FRCPC, SM(Epi), is with the University Health Network, the Sinai Health System, and the Faculty of Medicine, University of Toronto, Toronto, Ontario.
Charmaine Lok, MD, FRCPC, MSc, is with the University Health Network and the Faculty of Medicine, University of Toronto, Toronto, Ontario.
Chaim M Bell, MD, FRCPC, PhD, is with the University Health Network, the Sinai Health System, and the Faculty of Medicine, University of Toronto, Toronto, Ontario.
Marisa Battistella, BScPhm, PharmD, is with the University Health Network and the Leslie Dan Faculty of Pharmacy, University of Toronto, Toronto, Ontario.
University of Toronto · CAUniversity Health Network · CAHealth Net · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPatients receiving hemodialysis (HD) are at high risk of infections, including those caused by multidrug-resistant organisms. Given that antimicrobial exposure is a major risk factor for the emergence of these resistant organisms, minimizing inappropriate use is imperative. To optimize use, it is important to understand patterns of antimicrobial prescribing in this setting.

objectivesTo measure antimicrobial use and to describe prescribing patterns among patients receiving outpatient HD.

methodsA retrospective observational case series study was performed in an outpatient HD unit from February to April 2017. Adults for whom at least 1 antimicrobial was prescribed were included. The primary outcome was total antimicrobial days of therapy (DOT) per 1000 patient-days. Secondary outcomes were the characteristics of the antimicrobial prescriptions, in terms of antimicrobial class, indication, purpose, route, and prescriber group.

resultsAntimicrobials were prescribed for 53 (16%) of the 330 patients treated in the HD unit during the study period; the total number of prescriptions was 75. Antimicrobial use was 27.5 DOTs/1000 patient-days. Fluoroquinolones were the most frequently prescribed type of antimicrobial (

conclusionsAntimicrobial use was common in this study setting, with 1 in 6 HD patients receiving this type of medication. The findings of this study create opportunities to standardize antimicrobial prescribing at the local level for common infections that occur in patients receiving outpatient HD.

Indexed as

antimicrobialsantimicrobienshémodialysehemodialysisinfectious diseasesmaladies infectieusesprescribing patternsschémas de prescription

Identifiers

PMID34987258
PMCPMC8677003
OpenAlexW3174868730

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.