Evidence map›Paper›PMID 34987219›Full record

ArticleNature genetics2022

Author Correction: Gain-of-function variants in SYK cause immune dysregulation and systemic inflammation in humans and mice.

Lin Wang, Dominik Aschenbrenner, Zhiyang Zeng, Xiya Cao, Daniel Mayr, Meera Mehta, Melania Capitani, Neil Warner, Jie Pan, Liren Wang and 46 more

Open access · bronzeAbstract readPublished Erratum
PubMed Publisher
In one paragraph

Article in Nature genetics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.3field-weighted citation impact, top 50% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

56 authors at 20 institutions in 9 countries.

Lin Wang *Department of Gastroenterology, Pediatric Inflammatory Bowel Disease Research Center, Children's Hospital of Fudan University, Shanghai, China.ORCID http://orcid.org/0000-0002-1530-6542
Dominik Aschenbrenner *Translational Gastroenterology Unit and Biomedical Research Centre, Nuffield Department of Clinical Medicine, Experimental Medicine Division, University of Oxford, Oxford, UK.ORCID http://orcid.org/0000-0001-7580-2567
Zhiyang Zeng *Shanghai Key Laboratory of Regulatory Biology, Institute of Biomedical Sciences and School of Life Sciences, East China Normal University, Shanghai, China.
Xiya CaoShanghai Key Laboratory of Regulatory Biology, Institute of Biomedical Sciences and School of Life Sciences, East China Normal University, Shanghai, China.
Daniel MayrLudwig Boltzmann Institute for Rare and Undiagnosed Diseases, Vienna, Austria.
Meera MehtaSickKids Inflammatory Bowel Disease Center, Research Institute, Hospital for Sick Children, Toronto, Ontario, Canada.
Melania CapitaniTranslational Gastroenterology Unit and Biomedical Research Centre, Nuffield Department of Clinical Medicine, Experimental Medicine Division, University of Oxford, Oxford, UK.
Neil WarnerSickKids Inflammatory Bowel Disease Center, Research Institute, Hospital for Sick Children, Toronto, Ontario, Canada.ORCID http://orcid.org/0000-0002-9207-5979
Jie PanSickKids Inflammatory Bowel Disease Center, Research Institute, Hospital for Sick Children, Toronto, Ontario, Canada.
Liren WangShanghai Key Laboratory of Regulatory Biology, Institute of Biomedical Sciences, East China Normal University, Shanghai, China.
Qi LiSickKids Inflammatory Bowel Disease Center, Research Institute, Hospital for Sick Children, Toronto, Ontario, Canada.
Tao ZuoCenter for Gut Microbiota Research, The Chinese University of Hong Kong, Hong Kong, China.
Sarit Cohen-KedarFelsenstein Medical Research Center, Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.
Jiawei LuShanghai Key Laboratory of Regulatory Biology, Institute of Biomedical Sciences, East China Normal University, Shanghai, China.
Rico Chandra ArdyLudwig Boltzmann Institute for Rare and Undiagnosed Diseases, Vienna, Austria.
Daniel J MulderSickKids Inflammatory Bowel Disease Center, Research Institute, Hospital for Sick Children, Toronto, Ontario, Canada.ORCID http://orcid.org/0000-0003-2974-855X
Dilan DissanayakeDivision of Rheumatology, Department of Pediatrics, Hospital for Sick Children, Toronto, Ontario, Canada.
Kaiyue PengDepartment of Gastroenterology, Pediatric Inflammatory Bowel Disease Research Center, Children's Hospital of Fudan University, Shanghai, China.
Zhiheng HuangDepartment of Gastroenterology, Pediatric Inflammatory Bowel Disease Research Center, Children's Hospital of Fudan University, Shanghai, China.
Xiaoqin LiDepartment of Gastroenterology, Zhengzhou Children's Hospital, Zhengzhou, China.
Yuesheng WangDepartment of Gastroenterology, Zhengzhou Children's Hospital, Zhengzhou, China.
Xiaobing WangNeonate Department, Sanmenxia Central Hospital, Sanmenxia, China.
Shuchao LiDepartment of Pediatrics, Lushi County Renmin Hospital, Sanmenxia, China.
Samuel BullersTranslational Gastroenterology Unit and Biomedical Research Centre, Nuffield Department of Clinical Medicine, Experimental Medicine Division, University of Oxford, Oxford, UK.
Anís N GammageTranslational Gastroenterology Unit and Biomedical Research Centre, Nuffield Department of Clinical Medicine, Experimental Medicine Division, University of Oxford, Oxford, UK.ORCID http://orcid.org/0000-0002-7493-8988
Klaus WarnatzDepartment of Rheumatology and Clinical Immunology, Medical Center, Faculty of Medicine, University of Freiburg, Freiburg, Germany.
Ana-Iris SchieferDepartment of Clinical Pathology, Medical University Vienna, Vienna, Austria.
Gergely KrivanNational Institute of Hematology and Infectious Diseases, Department for Pediatric Hematology and Hemopoietic Stem Cell Transplantation, Central Hospital of Southern Pest, Budapest, Hungary.
Vera GodaNational Institute of Hematology and Infectious Diseases, Department for Pediatric Hematology and Hemopoietic Stem Cell Transplantation, Central Hospital of Southern Pest, Budapest, Hungary.
Walter H A KahrDepartment of Biochemistry, University of Toronto, Toronto, Ontario, Canada.ORCID http://orcid.org/0000-0002-2832-7158
Mathieu LemaireDepartment of Biochemistry, University of Toronto, Toronto, Ontario, Canada.
Genomics England Research Consortium
Chien-Yi LuDepartment of Biochemistry, University of Toronto, Toronto, Ontario, Canada.
Iram SiddiquiDivision of Pathology, Department of Pediatric Laboratory Medicine, University of Toronto, Toronto, Ontario, Canada.
Michael G SuretteDepartment of Medicine, Farncombe Family Digestion Health Institute, McMaster University, Hamilton, Ontario, Canada.ORCID http://orcid.org/0000-0003-0086-4995
Daniel KotlarzDepartment of Pediatrics, Dr. von Hauner Children's Hospital, University Hospital, Ludwig Maximilian University Munich, Munich, Germany.
Karin R EngelhardtTranslational and Clinical Research Institute, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne, UK.
Helen R GriffinTranslational and Clinical Research Institute, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne, UK.
Robert RottapelPrincess Margaret Cancer Centre, University Health Network, Department of Medical Biophysics, University of Toronto, Toronto, Ontario, Canada.
Hélène DecaluweDivision of Immunology and Rheumatology, Department of Pediatrics, Sainte-Justine University Hospital, Montreal, Quebec, Canada.
Ronald M LaxerDivision of Rheumatology, Department of Pediatrics, Hospital for Sick Children, Toronto, Ontario, Canada.
Michele ProiettiInstitute for Immunodeficiency, Center for Chronic Immunodeficiency (CCI), Medical Center, Faculty of Medicine, Albert-Ludwigs-University of Freiburg, Freiburg, Germany.
Sophie HambletonFaculty of Medical Sciences, 100KGP England, Newcastle University, Newcastle upon Tyne, UK.ORCID http://orcid.org/0000-0001-7954-3267
Suzanne ElcombeDepartment of Immunology, Royal Victoria Infirmary, The Newcastle upon Tyne Hospitals NHS Foundation Trust, Newcastle upon Tyne, UK.
Cong-Hui GuoSickKids Inflammatory Bowel Disease Center, Research Institute, Hospital for Sick Children, Toronto, Ontario, Canada.
Bodo GrimbacherInstitute for Immunodeficiency, Center for Chronic Immunodeficiency (CCI), Medical Center, Faculty of Medicine, Albert-Ludwigs-University of Freiburg, Freiburg, Germany.
Iris DotanDivision of Gastroenterology, Rabin Medical Center, Petah Tikva, Israel.
Siew C NgCenter for Gut Microbiota Research, The Chinese University of Hong Kong, Hong Kong, China.ORCID http://orcid.org/0000-0002-6850-4454
Spencer A FreemanDepartment of Biochemistry, University of Toronto, Toronto, Ontario, Canada.
Scott B SnapperDivision of Gastroenterology, Hepatology and Nutrition, Boston Children's Hospital, Boston, MA, USA.ORCID http://orcid.org/0000-0003-0267-4247
Christoph KleinDepartment of Pediatrics, Dr. von Hauner Children's Hospital, University Hospital, Ludwig Maximilian University Munich, Munich, Germany.ORCID http://orcid.org/0000-0003-0956-0445
Kaan Boztug *Ludwig Boltzmann Institute for Rare and Undiagnosed Diseases, Vienna, Austria.
Ying Huang *Department of Gastroenterology, Pediatric Inflammatory Bowel Disease Research Center, Children's Hospital of Fudan University, Shanghai, China. yhuang815@163.com.ORCID http://orcid.org/0000-0002-4931-4006
Dali Li *Shanghai Key Laboratory of Regulatory Biology, Institute of Biomedical Sciences and School of Life Sciences, East China Normal University, Shanghai, China. dlli@bio.ecnu.edu.cn.ORCID http://orcid.org/0000-0002-0046-8493
Holm H Uhlig *Translational Gastroenterology Unit and Biomedical Research Centre, Nuffield Department of Clinical Medicine, Experimental Medicine Division, University of Oxford, Oxford, UK.
Aleixo M Muise *SickKids Inflammatory Bowel Disease Center, Research Institute, Hospital for Sick Children, Toronto, Ontario, Canada. aleixo.muise@utoronto.ca.ORCID http://orcid.org/0000-0001-9624-3346
University of Toronto · CANewcastle University · GBEast China Normal University · CNSickKids Foundation · CAAustrian Academy of Sciences · ATChildren's Hospital of Fudan University · CNJohn Radcliffe Hospital · GBUniversity of Freiburg · DEChinese University of Hong Kong · HKLudwig-Maximilians-Universität München · DENational Center for Epidemiology · HUNuffield Orthopaedic Centre · GBTel Aviv University · ILZhengzhou Children's Hospital · CNBrigham and Women's Hospital · USCentre Hospitalier Universitaire Sainte-Justine · CAHospital for Sick Children · CAMcMaster University · CAMedical University of Vienna · ATOntario Institute for Cancer Research · CA

Funding

Wellcome Trust 207556/Z/17/Z
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Identifiers

PMID34987219
OpenAlexW4206666463

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.