Evidence map›Paper›PMID 34987195›Full record

ArticleEye (London, England)2022

Preliminary clinical validation of a new picture-based visual acuity test in children with amblyopia: a comparison of The Auckland Optotypes and crowded logMAR letters.

Emma M McVeigh, Siobhán M Ludden, Sahra Mohamed, Nilpa Shah, Pádraig J Mulholland, Annegret Dahlmann-Noor

Open access · hybridAbstract read
In one paragraph

Article in Eye (London, England), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.6field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 2 countries.

Emma M McVeighNational Institute for Health Research (NIHR) Biomedical Research Centre at Moorfields Eye Hospital NHS Foundation Trust and UCL Institute of Ophthalmology, London, UK.
Siobhán M LuddenNational Institute for Health Research (NIHR) Biomedical Research Centre at Moorfields Eye Hospital NHS Foundation Trust and UCL Institute of Ophthalmology, London, UK.
Sahra MohamedCommunity Eye Service, Cambridge Community Services, Bedford, UK.
Nilpa ShahNational Institute for Health Research (NIHR) Biomedical Research Centre at Moorfields Eye Hospital NHS Foundation Trust and UCL Institute of Ophthalmology, London, UK.
Pádraig J MulhollandNational Institute for Health Research (NIHR) Biomedical Research Centre at Moorfields Eye Hospital NHS Foundation Trust and UCL Institute of Ophthalmology, London, UK.
Annegret Dahlmann-NoorNational Institute for Health Research (NIHR) Biomedical Research Centre at Moorfields Eye Hospital NHS Foundation Trust and UCL Institute of Ophthalmology, London, UK. annegret.dahlmann-noor@nhs.net.
National Institute for Health Research · GBUniversity College London · GBCambridgeshire Community Services NHS Trust · GBMoorfields Eye Hospital NHS Foundation Trust · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND/

aimsAmblyopia is the most common visual deficit in children and accurate visual acuity (VA) assessment is essential for diagnosis. While ETDRS high-contrast logMAR VA is the reference standard test for adults, less agreement exists for pre-literate children. A new picture optotype acuity test (The Auckland Optotypes [TAO]) has shown favourable comparison to letter acuity charts but has not yet been evaluated in children with amblyopia. This study aimed to compare VA obtained using TAO to crowded logMAR letters in children age 5-8 years with amblyopia.

methodsChildren with amblyopia (n = 54 [20.37% strabismic, 18.52% anisometropic, 61.11% mixed], mean age 78.30 ± 11.72 months) were recruited from paediatric ophthalmology/orthoptic clinics at Moorfields Eye Hospital NHS Foundation Trust, London, and Cambridge Community Services NHS Trust, Bedford. Best-corrected VA was measured in both the amblyopic eye (AE) and fellow eye (FE) using TAO and a crowded letter acuity chart. Bland-Altman analysis was used to measure 95% limits of agreement (LoA) for VA measures captured (AE, FE and interocular difference [IOD]).

resultsGood agreement between TAO and letter VA measurement was observed (mean bias: AE -0.01, FE 0.01, IOD -0.02). For AE measures 95% LoA were from -0.25 to 0.24 logMAR, this being similar for FE (-0.24 to 0.25) and IOD measures (-0.30 to 0.27).

conclusionTAO and letters elicited similar VA in children with amblyopia. TAO could be a useful picture-based chart for paediatric vision assessment.

Indexed as

AmblyopiaAdultChildChild, PreschoolHumansOrthopticsReproducibility of ResultsVision TestsVisual Acuity

Identifiers

PMID34987195
PMCPMC9674699
OpenAlexW4205872384

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.