Evidence map›Paper›PMID 34986848›Full record

ArticleReproductive health2022

Factors associated with contraceptive use among women living with HIV in Canada: a controlled, cross-sectional study.

Chadni C Khondoker, Angela Kaida, Anna Marquez, Amber R Campbell, Hélène C F Côté, Arianne Y Albert, Neora Pick, Evelyn J Maan, Emilie A B Russell, Jerilynn C Prior and 4 more

Abstract read
In one paragraph

Article in Reproductive health, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Chadni C KhondokerFaculty of Medicine, University of British Columbia (UBC), Vancouver, BC, Canada.
Angela KaidaFaculty of Health Sciences, Simon Fraser University, Burnaby, BC, Canada.
Anna MarquezOak Tree Clinic, BC Women's Hospital, Vancouver, BC, Canada.
Amber R CampbellOak Tree Clinic, BC Women's Hospital, Vancouver, BC, Canada.
Hélène C F CôtéWomen's Health Research Institute, BC Women's Hospital, E600B-4500 Oak Street, Vancouver, BC, V6H 3N1, Canada.
Arianne Y AlbertWomen's Health Research Institute, BC Women's Hospital, E600B-4500 Oak Street, Vancouver, BC, V6H 3N1, Canada.
Neora PickFaculty of Medicine, University of British Columbia (UBC), Vancouver, BC, Canada.
Evelyn J MaanOak Tree Clinic, BC Women's Hospital, Vancouver, BC, Canada.
Emilie A B RussellFaculty of Medicine, University of British Columbia (UBC), Vancouver, BC, Canada.
Jerilynn C PriorWomen's Health Research Institute, BC Women's Hospital, E600B-4500 Oak Street, Vancouver, BC, V6H 3N1, Canada.
Chelsea ElwoodOak Tree Clinic, BC Women's Hospital, Vancouver, BC, Canada.
Jason BrophyDepartment of Pediatrics, Children's Hospital of Eastern Ontario, University of Ottawa, Ottawa, ON, Canada.
Melanie C M MurrayFaculty of Medicine, University of British Columbia (UBC), Vancouver, BC, Canada. Melanie.Murray@cw.bc.ca.ORCID http://orcid.org/0000-0001-9538-2758
CIHR team grant on Cellular Aging, H. I. V. Comorbidities in Women, Children (CARMA), (CIHR HIV Clinical Trials Network study 277)

Funding

canadian hiv trials network, canadian institutes of health research CTN 777canadian institute of health research TCO-125269
6 · The paper itself

Abstract

backgroundMultiple contraindications to combined hormonal contraceptives (CHC) use exist. The impact of these factors on contraceptive choice, particularly among women living with HIV (WLWH), is not well understood. We measured and compared the prevalence of contraceptive use and contraindications among WLWH and women not living with HIV (controls).

methodsWe examined cross-sectional survey and medical chart data from 83 WLWH and 62 controls, aged 16-49 and sexually active, from 2013-2017. We compared the age-adjusted prevalence and types of contraceptives used in the last month and the proportion of women with CHC contraindications, including drug interactions, medical comorbidities, and smoking at ≥ 35 years old. All WLWH received care at an interdisciplinary, women-centred HIV clinic.

resultsCompared to controls, WLWH were older (median [IQR)] 39 [34-43] vs 31 [23-41] years; p = 0.003), had less post-secondary education (37% vs 73%; p < 0.001), and more often had household income < $15,000/year (49% vs 30%; p = 0.006). WLWH trended to higher contraceptive prevalence than controls (80% vs 63%; p = 0.06 adjusted for age). Overall hormonal contraceptive use was similar. However, despite controlling for age, WLWH used CHC less (4% vs 18%; p = 0.006) than controls, and had more frequently undergone tubal ligation (12% vs 2%; p = 0.03). WLWH also experienced more CHC contraindications (54% vs 13%; p = 0.0001), including smoking at ≥ 35 years old (30% vs 6%; p = 0.0003) or a CHC-related drug interaction (all antiretroviral related) (25% vs 0%; p = 0.0001).

conclusionsWLWH attending our interdisciplinary clinic used hormonal contraception at similar rates as controls, though with different types. Differences may reflect different distributions of CHC contraindications. CHC contraindications present barriers to accessing the full range of contraceptive choices for WLWH. Guidelines and education for care providers and WLWH regarding contraceptive choices and drug interactions are needed, especially when care is provided without the benefit of an interdisciplinary women-centered healthcare team.

Indexed as

Contraceptive AgentsHIV InfectionsAdultChild, PreschoolContraceptionContraceptive DevicesCross-Sectional StudiesFemaleHumansContraceptive AgentsCanadaContraceptionHIVWomen

Identifiers

PMID34986848
PMCPMC8729076

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.