Evidence map›Paper›PMID 34986700›Full record

ArticleJournal of primary care & community health

Symptoms COVID 19 Positive Vapers Compared to COVID 19 Positive Non-vapers.

David D McFadden, Shari L Bornstein, Robert Vassallo, Bradley R Salonen, Mohammed Nadir Bhuiyan, Darrell R Schroeder, Ivana T Croghan

Abstract read
In one paragraph

Article in Journal of primary care & community health. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. The Impact of the COVID-19 Pandemic on Adolescent Mental Health and Substance Use.The Journal of adolescent health : official publication of the Society for Adolescent Medicine · 2022
    Trial
  4. Article
  5. Vaping-related lung disease: a narrative review.Journal of thoracic disease · 2026
    Review
  6. Article
  7. Article
  8. Review
  9. Review
  10. Development of Chatbot-Assisted Smoking Cessation Telehealth Intervention: A Case Report.AMIA ... Annual Symposium proceedings. AMIA Symposium · 2024
    Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Electronic Cigarettes: A Pro-Con Review of the Current Literature.The journal of allergy and clinical immunology. In practice · 2022
    Review
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

David D McFaddenMayo Clinic, Rochester, MN, USA.
Shari L BornsteinMayo Clinic, Rochester, MN, USA.
Robert VassalloMayo Clinic, Rochester, MN, USA.
Bradley R SalonenMayo Clinic, Rochester, MN, USA.
Mohammed Nadir BhuiyanMayo Clinic, Rochester, MN, USA.
Darrell R SchroederMayo Clinic, Rochester, MN, USA.
Ivana T CroghanMayo Clinic, Rochester, MN, USA.ORCID 0000-0003-3464-3525

Funding

Mayo Clinic Center for Clinical and Translational Science (CCaTS UL1 Supplement - Dr. Timothy Curry)UL1TR002377 · NCATS · MAYO CLINIC ROCHESTER · PI VESNA D GAROVIC · 2017 to 2026
$78.4M
NCATS NIH HHS UL1 TR002377
6 · The paper itself

Abstract

objectivesThe purpose of the present study was to assess and describe the severity of symptoms reported by Covid-19 positive patients who vaped (smoked e-cigarettes) when compared to those who did not vape or smoke at the time of the diagnosis of Covid-19.

methodsPatients from this study are from a well-characterized patient cohort collected at Mayo Clinic between March 1, 2020 and February 28, 2021; with confirmed COVID-19 diagnosis defined as a positive result on reverse-transcriptase-polymerase-chain-reaction (RT-PCR) assays from nasopharyngeal swab specimens. Among the 1734 eligible patients, 289 patients reported current vaping. The cohort of vapers (N = 289) was age and gender matched to 1445 covid-19 positive patients who did not vape. The data analyzed included: date of birth, gender, ethnicity, race, marital status, as well as lifestyle history such as vaping and smoking and reported covid-19 symptoms experienced.

resultsA logistic regression analysis was performed separately for each symptom using generalized estimating equations (GEE) with robust variance estimates in order to account for the 1:5 age, sex, and race matched set study design. Patients who vaped and developed Covid-19 infection were more likely to have chest pain or tightness (16% vs 10%, vapers vs non vapers,

conclusionVapers experience higher frequency of covid-19 related symptoms when compared with age and gender matched non-vapers. Further work should examine the impact vaping has on post-covid symptom experience.

Indexed as

COVID-19Electronic Nicotine Delivery SystemsCOVID-19 TestingHumansSARS-CoV-2Smokerscovid-19e-cigarettesvaping

Identifiers

PMID34986700
PMCPMC8744181

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.