Evidence map›Paper›PMID 34986675›Full record

ArticleThe Journal of international medical research2022

Gastric adenocarcinoma with germ cell tumor components: a rare case report.

Xu Han, Shu Wang, Hongyu He, Yao Sun, Jiannan Li

Open access · goldAbstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in The Journal of international medical research, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 99% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Xu HanDepartment of General Surgery, The Second Hospital of Jilin University, Changchun, Jilin, China.
Shu WangDepartment of Radiotherapy, The Second Hospital of Jilin University, Changchun, Jilin, China.
Hongyu HeOperating Theater and Department of Anesthesiology, The Second Hospital of Jilin University, Changchun, Jilin, China.
Yao SunDepartment of General Surgery, The Second Hospital of Jilin University, Changchun, Jilin, China.
Jiannan LiDepartment of General Surgery, The Second Hospital of Jilin University, Changchun, Jilin, China.ORCID https://orcid.org/0000-0001-9744-7666
Second Affiliated Hospital of Jilin University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Germ cell tumors (GCTs) often occur in male testes and female ovaries. Extragonadal GCTs account for approximately 2% to 5% of all GCTs and mainly occur in the mediastinum, retroperitoneum, and pineal gland. In this study, we reported a rare case of gastric adenocarcinoma with GCT components. The patient's serum α-fetoprotein (AFP) level was higher than normal. Abdominal computed tomography (CT) showed a 10-cm × 10-cm tumor between the spleen and the bottom of the stomach. Gastric endoscopy indicated an ulcerative lesion extending from the bottom of the stomach to the antrum. Tissue biopsy identified the tumor as an adenocarcinoma. The patient underwent abdominal tumor resection, subtotal gastrectomy, D2 lymphadenectomy, and splenectomy. Postoperative histopathology showed that the tumor was a moderately to poorly differentiated adenocarcinoma. Immunohistochemistry analysis revealed positive staining for AFP, glypican-3, and placental alkaline phosphatase. Gastric adenocarcinoma with GCT components is particularly uncommon and rarely reported. Elevated serum AFP and/or β-human chorionic gonadotropin levels, abdominal CT, histopathology, and immunohistochemistry may help diagnose GCTs. Radical surgery resection is the primary treatment method for GCTs. Adjuvant chemotherapy and radiotherapy are effective for advanced GCTs.

Indexed as

AdenocarcinomaNeoplasms, Germ Cell and EmbryonalStomach Neoplasmsalpha-FetoproteinsChorionic Gonadotropin, beta Subunit, HumanFemaleHumansMalePlacentaPregnancyalpha-FetoproteinsChorionic Gonadotropin, beta Subunit, Humancase reportextragonadal germ cell tumorgastric adenocarcinomaGerm cell tumorradical surgeryα-fetoprotein

Identifiers

PMID34986675
PMCPMC8743960
OpenAlexW4206290921

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.