Evidence map›Paper›PMID 34986538›Full record

ReviewZhejiang da xue xue bao. Yi xue ban = Journal of Zhejiang University. Medical sciences2021

Progress on the application of positron emission tomography imaging of cannabinoid type 1 receptor in neuropsychiatric diseases.

Lijuan Ma, Shuang Wu, Kai Zhang, Mei Tian, Hong Zhang

Open access · bronzeAbstract readReview
In one paragraph

Review in Zhejiang da xue xue bao. Yi xue ban = Journal of Zhejiang University. Medical sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 91% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 2 countries.

Lijuan Ma4. College of Biomedical Engineering and Instrument Science, Zhejiang University, Hangzhou 310027, China.
Shuang Wu4. College of Biomedical Engineering and Instrument Science, Zhejiang University, Hangzhou 310027, China.
Kai Zhang4. College of Biomedical Engineering and Instrument Science, Zhejiang University, Hangzhou 310027, China.
Mei Tian4. College of Biomedical Engineering and Instrument Science, Zhejiang University, Hangzhou 310027, China.
Hong Zhang4. College of Biomedical Engineering and Instrument Science, Zhejiang University, Hangzhou 310027, China.
Second Affiliated Hospital of Zhejiang University · CNRIKEN Center for Biosystems Dynamics Research · JPZhejiang University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cannabinoid type 1 receptor (CB1R), as the major member of the endocannabinoid system, is among the most abundant receptors expressed in the central nervous system. CB1R is mainly located on the axon terminals of presynaptic neurons and participate in the modulation of neuronal excitability and synaptic plasticity, playing an important role in the pathogenesis of various neuropsychiatric diseases. In recent years, the consistent development of CB1R radioligands and the maturity of molecular imaging techniques, particularly positron emission tomography (PET) may help to visualize the expression and distribution of CB1R in central nervous system . At present, CB1R PET imaging can effectively evaluate the changes of CB1R levels in neuropsychiatric diseases such as Huntington's disease and schizophrenia, and its correlation with the disease severity, therefore providing new insights for the diagnosis and treatment of neuropsychiatric diseases. This article reviews the application of CB1R PET imaging in Alzheimer's disease, Parkinson's disease, Huntington's disease, schizophrenia, post-traumatic stress disorder, cannabis use disorder and depression.

Indexed as

CannabinoidsReceptor, Cannabinoid, CB1HumansMental DisordersNeurodegenerative DiseasesNeuronsPositron-Emission TomographyCannabinoidsReceptor, Cannabinoid, CB1Cannabinoid type 1 receptorMental diseasePositron emission tomographyrative diseaseReviewSchizophrenia

Identifiers

PMID34986538
PMCPMC8732249
OpenAlexW3194850555

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.