Evidence map›Paper›PMID 34986482›Full record

ArticleMedical principles and practice : international journal of the Kuwait University, Health Science Centre2022

COVID-19 and the Human Eye: Conjunctivitis, a Lone COVID-19 Finding - A Case-Control Study.

Valeria Mocanu, Dharmesh Bhagwani, Abhinav Sharma, Claudia Borza, Ciprian Ilie Rosca, Morariu Stelian, Shalini Bhagwani, Laura Haidar, Lajwanti Kshtriya, Nilima Rajpal Kundnani and 2 more

Open access · diamondAbstract read
In one paragraph

Article in Medical principles and practice : international journal of the Kuwait University, Health Science Centre, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
2.9field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it, 14 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 4 institutions in 2 countries.

Valeria MocanuDepartment of Ophthalmology, EYE-ENT Senzory-Tumoral Research Centre, Victor Babeș University of Medicine and Pharmacy Timisoara, Timisoara, Romania.
Dharmesh BhagwaniAMC MET Medical College, LG Hospital, Ahmedabad, India.
Abhinav SharmaDepartment of Cardiology, Victor Babes University of Medicine and Pharmacy Timisoara, Timisoara, Romania.
Claudia BorzaDepartment of Functional Science, Discipline of Physiopathology, Center for Translational Research and Systems Medicine, Victor Babes University of Medicine and Pharmacy, Timisoara, Romania.
Ciprian Ilie RoscaFamily Physician Clinic, Teremia Mare, Romania.
Morariu StelianDepartment of Occupational Medicine, Municipal Emergency University Hospital, Arad, Romania.
Shalini BhagwaniESIC Hospital, Ahmedabad, India.
Laura HaidarDepartment of Functional Sciences, Physiology, Centre of Immuno-Physiology and Biotechnologies, Victor Babes University of Medicine and Pharmacy, Timisoara, Romania.
Lajwanti KshtriyaShreeji Clinic, Ahmedabad, India.
Nilima Rajpal KundnaniFamily Physician Clinic, Teremia Mare, Romania.
Florin-Raul HorhatDepartment of Functional Science, Medical Informatics and Biostatistics, "Victor Babeș" University of Medicine and Pharmacy Timisoara, Timisoara, Romania.
Raluca HorhatDepartment of Functional Science, Biophysics, "Victor Babeș" University of Medicine and Pharmacy Timisoara, Timisoara, Romania.
Victor Babeș University of Medicine and Pharmacy Timișoara · ROArad County Clinical Hospital · ROB.J. Medical College · INESIC Hospital · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesCOVID-19 has varied clinical manifestations, from asymptomatic to severe cases, and conjunctivitis is one of them, but sometimes a lone initial symptom is found to be present. The aim of this study was to identify the prevalence of conjunctivitis as the first symptom in COVID-19 patients in a primary healthcare unit. METHODOLOGY: A retrospective study was conducted, analyzing the presenting complains/symptoms and results of COVID-19-confirmatory tests.

resultsOut of the 672 cases that were sent for RT-PCR testing, only 121 (18%) were found to be positive. Among these, 2.67% patients had both conjunctivitis and COVID-19, 77.77% patients had unilateral eye affected, while 22.22% had bilateral conjunctivitis of varying degrees. Fifteen patients diagnosed to have both acute conjunctivitis and COVID-19 presented other symptoms associated with COVID-19 infection. Three patients had only acute conjunctivitis during their entire course of COVID-19.

conclusionsConjunctivitis is a symptom of COVID-19 and may be the first sign of the infection, until the onset of the classical manifestations; such patients may continue to be a viral reservoir. Physicians should not miss unilateral conjunctivitis as it can be the only presenting complaint of COVID-19 during the initial phase, which might worsen if undetected and can aid in the spread of the contagion.

Indexed as

AdultCase-Control StudiesConjunctivitisCOVID-19COVID-19 Nucleic Acid TestingEyeFemaleHumansMaleMiddle AgedPrevalenceRetrospective StudiesRNA, ViralSARS-CoV-2Young AdultRNA, ViralConjunctivitisCorona virus disease-2019Prevalence

Identifiers

PMID34986482
PMCPMC8995668
OpenAlexW4205964966

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.