ArticleCell reports2022
Differential coding of goals and actions in ventral and dorsal corticostriatal circuits during goal-directed behavior.
Article in Cell reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
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Who cites it
24 citing papers in PubMed.
- Reversed functional gradient in primate prefrontal cortex: Posterior dominance and frontopolar task-related deactivation.Science advances · 2026Article
- Long-term Learning Induces Plastic Changes in Frontostriatal Circuits.bioRxiv : the preprint server for biology · 2026Article
- Spatiotemporal Decoding of Explore-Exploit Decisions in the Human Brain.bioRxiv : the preprint server for biology · 2026Article
- Synaptic pruning, myelination and the emergence of psychiatric disorders in late adolescence.bioRxiv : the preprint server for biology · 2026Article
- Prefrontal modulation of striatal engagement: a hierarchical framework for goal-directed behavior.Communications biology · 2026Review
- Article
- Contribution of amygdala to dynamic model arbitration under uncertainty.Nature communications · 2025Article
- Ventral striatal astrocytes contribute to reinforcement learning.bioRxiv : the preprint server for biology · 2025Article
- Reward-reset interval timing drives patch foraging decisions through neural state transitions in dorsomedial striatum.bioRxiv : the preprint server for biology · 2025Article
- Genetic changes linked to two different syndromic forms of autism enhance reinforcement learning in early adolescent male but not female mice.bioRxiv : the preprint server for biology · 2025Article
- Ventral frontostriatal circuitry mediates the computation of reinforcement from symbolic gains and losses.Neuron · 2024Article
- Article
- Brain mechanism of foraging: Reward-dependent synaptic plasticity versus neural integration of values.Proceedings of the National Academy of Sciences of the United States of America · 2024Article
- Neurons in the monkey frontopolar cortex encode learning stage and goal during a fast learning task.PLoS biology · 2024Article
- Latent-state and model-based learning in PTSD.Trends in neurosciences · 2024Review
- Motor System-Dependent Effects of Amygdala and Ventral Striatum Lesions on Explore-Exploit Behaviors.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2024Article
- Spectral learning of Bernoulli linear dynamical systems models.Transactions on machine learning research · 2023Article
- Pathways to the persistence of drug use despite its adverse consequences.Molecular psychiatry · 2023Review
- Electrophysiological Markers of Aberrant Cue-Specific Exploration in Hazardous Drinkers.Computational psychiatry (Cambridge, Mass.) · 2023Article
- What Does the Frontopolar Cortex Contribute to Goal-Directed Cognition and Action?The Journal of neuroscience : the official journal of the Society for Neuroscience · 2022Review
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4 authors.
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Abstract
Goal-directed behavior requires identifying objects in the environment that can satisfy internal needs and executing actions to obtain those objects. The current study examines ventral and dorsal corticostriatal circuits that support complementary aspects of goal-directed behavior. We analyze activity from the amygdala, ventral striatum, orbitofrontal cortex, and lateral prefrontal cortex (LPFC) while monkeys perform a three-armed bandit task. Information about chosen stimuli and their value is primarily encoded in the amygdala, ventral striatum, and orbitofrontal cortex, while the spatial information is primarily encoded in the LPFC. Before the options are presented, information about the to-be-chosen stimulus is represented in the amygdala, ventral striatum, and orbitofrontal cortex; at the time of choice, the information is passed to the LPFC to direct a saccade. Thus, learned value information specifying behavioral goals is maintained throughout the ventral corticostriatal circuit, and it is routed through the dorsal circuit at the time actions are selected.
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