ArticlePLoS neglected tropical diseases2022
Transmission and containment of the SARS-CoV-2 Delta variant of concern in Guangzhou, China: A population-based study.
Article in PLoS neglected tropical diseases, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 4 of them syntheses that pooled it.
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Who cites it
21 citing papers in PubMed, 4 syntheses or guidelines pooled it.
- Assessing changes in incubation period, serial interval, and generation time of SARS-CoV-2 variants of concern: a systematic review and meta-analysis.BMC medicine · 2023Pooled it
- Rapid review and meta-analysis of serial intervals for SARS-CoV-2 Delta and Omicron variants.BMC infectious diseases · 2023Pooled it
- Clinical manifestations of COVID-19 breakthrough infections: A systematic review and meta-analysis.Journal of medical virology · 2022Pooled it
- Incubation Period of COVID-19 Caused by Unique SARS-CoV-2 Strains: A Systematic Review and Meta-analysis.JAMA network open · 2022Pooled it
- Trends and Core Competence Shifts in Nurses' Infectious Disease Emergency Response Competence Across COVID-19 Pandemic Phases: Repeated Cross-Sectional Survey and Network Analysis.JMIR public health and surveillance · 2026Article
- The optimal spatially-dependent control measures to effectively and economically eliminate emerging infectious diseases.PLoS computational biology · 2024Article
- Demographic Characteristics of Unvaccinated Asymptomatic and Symptomatic SARS-CoV-2 Cases in Barwon South West, Victoria, Australia.Pathogens (Basel, Switzerland) · 2023Article
- Transmissibility of severe acute respiratory syndrome coronavirus 2 among household contacts of coronavirus disease 2019-positive patients: A community-based study in India.Influenza and other respiratory viruses · 2023Article
- Genomic epidemiology of SARS-CoV-2 from Uttar Pradesh, India.Scientific reports · 2023Article
- Genomic epidemiology of SARS-CoV-2 variants during the first two years of the pandemic in Colombia.Communications medicine · 2023Article
- Evaluation of the EsteR Toolkit for COVID-19 Decision Support: Sensitivity Analysis and Usability Study.JMIR formative research · 2023Article
- SARS-CoV-2 incubation period across variants of concern, individual factors, and circumstances of infection in France: a case series analysis from the ComCor study.The Lancet. Microbe · 2023Article
- Epidemiological characteristics and transmission dynamics of the outbreak caused by the SARS-CoV-2 Omicron variant in Shanghai, China: A descriptive study.The Lancet regional health. Western Pacific · 2022Article
- Risk factors for severe Covid-19 breakthrough infections: an observational longitudinal study.BMC infectious diseases · 2022Observational
- The Association Between Clinical Severity and Incubation Period of SARS-CoV-2 Delta Variants: Retrospective Observational Study.JMIR public health and surveillance · 2022Observational
- SARS-CoV-2 infection in pediatric population before and during the Delta (B.1.617.2) and Omicron (B.1.1.529) variants era.Virology journal · 2022Review
- An assessment of transmission dynamics via time-varying reproduction number of the second wave of the COVID-19 epidemic in Fiji.Royal Society open science · 2022Article
- Genomic epidemiology of Delta SARS-CoV-2 during transition from elimination to suppression in Aotearoa New Zealand.Nature communications · 2022Article
- Epidemiological characteristics and transmission dynamics of the outbreak caused by the SARS-CoV-2 Omicron variant in Shanghai, China: a descriptive study.medRxiv : the preprint server for health sciences · 2022Article
- Shorter Incubation Period among Unvaccinated Delta Variant Coronavirus Disease 2019 Patients in Japan.International journal of environmental research and public health · 2022Article
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15 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe first community transmission of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Delta variant of concern (VOC) in Guangzhou, China occurred between May and June 2021. Herein, we describe the epidemiological characteristics of this outbreak and evaluate the implemented containment measures against this outbreak. METHODOLOGY/PRINCIPAL
findingsGuangzhou Center for Disease Control and Prevention provided the data on SARS-CoV-2 infections reported between 21 May and 24 June 2021. We estimated the incubation period distribution by fitting a gamma distribution to the data, while the serial interval distribution was estimated by fitting a normal distribution. The instantaneous effective reproductive number (Rt) was estimated to reflect the transmissibility of SARS-CoV-2. Clinical severity was compared for cases with different vaccination statuses using an ordinal regression model after controlling for age. Of the reported local cases, 7/153 (4.6%) were asymptomatic. The median incubation period was 6.02 (95% confidence interval [CI]: 5.42-6.71) days and the means of serial intervals decreased from 5.19 (95% CI: 4.29-6.11) to 3.78 (95% CI: 2.74-4.81) days. The incubation period increased with age (P<0.001). A hierarchical prevention and control strategy against COVID-19 was implemented in Guangzhou, with Rt decreasing from 6.83 (95% credible interval [CrI]: 3.98-10.44) for the 7-day time window ending on 27 May 2021 to below 1 for the time window ending on 8 June and thereafter. Individuals with partial or full vaccination schedules with BBIBP-CorV or CoronaVac accounted for 15.3% of the COVID-19 cases. Clinical symptoms were milder in partially or fully vaccinated cases than in unvaccinated cases (odds ratio [OR] = 0.26 [95% CI: 0.07-0.94]). CONCLUSIONS/SIGNIFICANCE: The hierarchical prevention and control strategy against COVID-19 in Guangzhou was timely and effective. Authorised inactivated vaccines are likely to contribute to reducing the probability of developing severe disease. Our findings have important implications for the containment of COVID-19.
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