Evidence map›Paper›PMID 34986003›Full record

ArticleApplied and environmental microbiology2022

Citizen Science Surveillance of Triazole-Resistant

Jennifer M G Shelton, Roseanna Collins, Christopher B Uzzell, Asmaa Alghamdi, Paul S Dyer, Andrew C Singer, Matthew C Fisher

Open access · hybridAbstract read
In one paragraph

Article in Applied and environmental microbiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed
3.5field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 40 citations in OpenAlex.

  1. Review
  2. Thermal adaptation crosstalk with azole response through lncRNA inbioRxiv : the preprint server for biology · 2026
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  6. Azole Resistance inOpen forum infectious diseases · 2026
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  8. Global epidemiology of azole resistance inJAC-antimicrobial resistance · 2026
    Review
  9. Article
  10. Review
  11. Recent developments inMicrobiology and molecular biology reviews : MMBR · 2025
    Review
  12. Refractory versus resistant invasive aspergillosis.The Journal of antimicrobial chemotherapy · 2025
    Review
  13. An approach to making life sciences FAIR-FAIR-DS as a tool for Aspergillus fumigatus.Database : the journal of biological databases and curation · 2025
    Article
  14. Article
  15. Climate Change Impacts on Environmental Fungi: Human Health and Fungal Disease.Current topics in microbiology and immunology · 2025
    Review
  16. Article
  17. Review
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 1 country.

Jennifer M G SheltonMRC Centre for Global Infectious Disease Analysis, Department of Infectious Disease Epidemiology, Imperial College Londongrid.7445.2, London, UK.ORCID 0000-0003-1429-6845
Roseanna CollinsSchool of Biosciences, University of Birminghamgrid.6572.6, Birmingham, UK.
Christopher B UzzellMRC Centre for Global Infectious Disease Analysis, Department of Infectious Disease Epidemiology, Imperial College Londongrid.7445.2, London, UK.
Asmaa AlghamdiSchool of Life Sciences, University of Nottinghamgrid.4563.4, Nottingham, UK.
Paul S DyerSchool of Life Sciences, University of Nottinghamgrid.4563.4, Nottingham, UK.
Andrew C SingerUK Centre for Ecology & Hydrology, Wallingford, UK.
Matthew C FisherMRC Centre for Global Infectious Disease Analysis, Department of Infectious Disease Epidemiology, Imperial College Londongrid.7445.2, London, UK.ORCID 0000-0002-1862-6402
London Centre for Neglected Tropical Disease Research · GBUK Centre for Ecology & Hydrology · GBUniversity of Nottingham · GBUniversity of Birmingham · GB

Funding

Medical Research Council MR/R015600/1UKRI | Medical Research Council (MRC) MR/R015600/1
6 · The paper itself

Abstract

Compost is an ecological niche for Aspergillus fumigatus due to its role as a decomposer of organic matter and its ability to survive the high temperatures associated with the composting process. Subsequently, composting facilities are associated with high levels of A. fumigatus spores that are aerosolized from compost and cause respiratory illness in workers. In the UK, gardening is an activity enjoyed by individuals of all ages, and it is likely that they are being exposed to A. fumigatus spores when handling commercial compost or compost they have produced themselves. In the present study, 246 citizen scientists collected 509 soil samples from locations in their gardens in the UK, from which were cultured 5,174 A. fumigatus isolates. Of these isolates, 736 (14%) were resistant to tebuconazole: the third most-sprayed triazole fungicide in the UK, which confers cross-resistance to the medical triazoles used to treat A. fumigatus lung infections in humans. These isolates were found to contain the common resistance mechanisms in the A. fumigatus

Indexed as

Aspergillus fumigatusCitizen ScienceAntifungal AgentsAzolesDrug Resistance, FungalFungal ProteinsGardeningGardensHumansMicrobial Sensitivity TestsSoilTriazolesAntifungal AgentsAzolesFungal ProteinsSoilTriazolesDNA sequencingdrug resistance mechanismsenvironmental microbiologymolecular geneticsmycologypublic health

Identifiers

PMID34986003
PMCPMC8862786
OpenAlexW4213296771

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.