ArticleJCO clinical cancer informatics2022
eSyM: An Electronic Health Record-Integrated Patient-Reported Outcomes-Based Cancer Symptom Management Program Used by Six Diverse Health Systems.
Article in JCO clinical cancer informatics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03850912 (SIMPRO Research Center), which is not on this map. Cited by 50 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
SIMPRO Research Center: Integration and Implementation of PROs for Symptom Management in Oncology Practice
Who cites it
50 citing papers in PubMed.
- Patient and staff experiences with an EHR-Integrated Symptom Management Program (eSyM) in oncology.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2025Trial
- Strategies for implementing an electronic patient-reported outcomes-based symptom management program across six cancer centers.BMC health services research · 2024Trial
- Effects of a change in recall period on reporting severe symptoms: an analysis of a pragmatic multisite trial.Journal of the National Cancer Institute · 2024Trial
- Patient Experiences With a Symptom Monitoring and Self-Referral Program for Specialty Palliative Care After Lung Cancer Diagnosis: Qualitative Study.JMIR formative research · 2026Article
- Bridging the data latency gap: automated extraction of genomic biomarkers from unstructured clinical documents to support real-world oncology data.Cancer causes & control : CCC · 2026Article
- Real-world implementation of electronic patient-reported outcome measures (ePROMs) in routine oncology practice: a scoping review.ESMO real world data and digital oncology · 2026Review
- SiMON-PRO-Hematology®: Digital techology for pharmacotherapeutic and patient reported outcomes monitoring in patients with hematologic malignancies.Exploratory research in clinical and social pharmacy · 2026Article
- Implementation and Evaluation of a Social Networking Service-Based Mobile Patient-Generated Health Data System With Direct Electronic Medical Record Integration: Prospective Observational Study.JMIR medical informatics · 2026Observational
- Review
- Staff Perspectives on Normalizing and Sustaining Electronic Patient-Reported Outcomes Monitoring at Six US Health Systems.JCO oncology practice · 2026Article
- Longitudinal Patterns of Symptoms in Patients Undergoing Chemotherapy: A Secondary Analysis of a Cluster Randomized Clinical Trial.JAMA network open · 2026Observational
- Usability and Acceptance Testing of an Electronic Patient-Reported Outcome Symptom Monitoring System for People Receiving Immune Checkpoint Inhibitors: Mixed Methods Study.JMIR formative research · 2026Article
- Adaptation of digital integration of PROMs and PREMs in oncology during implementation: a scoping review.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026Article
- Evaluating the Feasibility of an Electronic Patient-Reported Outcomes Platform Integrating Electronic Health Records and a Mobile Messaging App in Breast Cancer Radiotherapy: Retrospective Cross-Sectional Study.JMIR mHealth and uHealth · 2026Article
- Shared Decision Making, Decision Aids and Patient Reported Outcome Measures for Overactive Bladder Care: A Review.Current bladder dysfunction reports · 2026Review
- Obtaining Patient-Reported Outcome Data via a Home Patient Monitoring App: Development, Implementation, and Validation of Novel Interface Terminology.JMIR mHealth and uHealth · 2025Article
- Article
- Implementation of Symptom Monitoring With Electronic Patient-Reported Outcomes: Perspectives and Recommendations From Community Oncology Practices (Alliance AFT-39).JCO oncology practice · 2025Article
- Assessing Quality of Life and Symptoms in Transplantation and CAR-T Recipients: Expert Panel Recommendations from the Survivorship Special Interest Group of ASTCT.Transplantation and cellular therapy · 2025Review
- Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
13 authors.
Funding
Abstract
purposeCollecting patient-reported outcomes (PROs) can improve symptom control and quality of life, enhance doctor-patient communication, and reduce acute care needs for patients with cancer. Digital solutions facilitate PRO collection, but without robust electronic health record (EHR) integration, effective deployment can be hampered by low patient and clinician engagement and high development and deployment costs. The important components of digital PRO platforms have been defined, but procedures for implementing integrated solutions are not readily available.
methodsAs part of the NCI's IMPACT consortium, six health care systems partnered with Epic to develop an EHR-integrated, PRO-based electronic symptom management program (eSyM) to optimize postoperative recovery and well-being during chemotherapy. The agile development process incorporated user-centered design principles that required engagement from patients, clinicians, and health care systems. Whenever possible, the system used validated content from the public domain and took advantage of existing EHR capabilities to automate processes.
resultseSyM includes symptom surveys on the basis of the PRO-Common Terminology Criteria for Adverse Events (PRO-CTCAE) plus two global wellness questions; reminders and symptom self-management tip sheets for patients; alerts and symptom reports for clinicians; and population management dashboards. EHR dependencies include a secure Health Insurance Portability and Accountability Act-compliant patient portal; diagnosis, procedure and chemotherapy treatment plan data; registries that identify and track target populations; and the ability to create reminders, alerts, reports, dashboards, and charting shortcuts.
conclusioneSyM incorporates validated content and leverages existing EHR capabilities. Build challenges include the innate technical limitations of the EHR, the constrained availability of site technical resources, and sites' heterogenous EHR configurations and policies. Integration of PRO-based symptom management programs into the EHR could help overcome adoption barriers, consolidate clinical workflows, and foster scalability and sustainability. We intend to make eSyM available to all Epic users.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.