Evidence map›Paper›PMID 34985663›Full record

ArticleMethods in molecular biology (Clifton, N.J.)2022

Hematopoietic Stem and Progenitor Cells (HSPCs).

Valeri H Terry, Gretchen E Zimmerman, Maria C Virgilio, Mark M Painter, Dale Bixby, Kathleen L Collins

Abstract read
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In one paragraph

Article in Methods in molecular biology (Clifton, N.J.), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Valeri H TerryDepartment of Internal Medicine, University of Michigan, Ann Arbor, MI, USA.
Gretchen E ZimmermanDepartment of Internal Medicine, University of Michigan, Ann Arbor, MI, USA.
Maria C VirgilioCellular and Molecular Biology Program, University of Michigan, Ann Arbor, MI, USA.
Mark M PainterGraduate Program in Immunology, University of Michigan, Ann Arbor, MI, USA.
Dale BixbyDepartment of Internal Medicine, University of Michigan, Ann Arbor, MI, USA.
Kathleen L CollinsDepartment of Internal Medicine, University of Michigan, Ann Arbor, MI, USA. klcollin@med.umich.edu.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cord blood is a readily available source of hematopoietic stem and progenitor cells (HSPCs) which can be infected with HIV-1 in vitro to produce inducible latently infected cells for reactivation studies. Infected HSPCs can also be found in the setting of clinically undetectable viremia in vivo. Here we describe an in vitro infection model utilizing cord blood derived HSPCs, as well as methods for isolating and characterizing provirus from bone marrow HSPCs from suppressed patients.

Indexed as

Hematopoietic Stem CellsHIV-1Fetal BloodHumansProvirusesViremiaHIV-1HSPCLatencyReactivationReservoir

Identifiers

PMID34985663

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.