Evidence map›Paper›PMID 34985643›Full record

ReviewScience China. Life sciences2022

Neural circuit control of innate behaviors.

Wei Xiao, Zhuo-Lei Jiao, Esra Senol, Jiwei Yao, Miao Zhao, Zheng-Dong Zhao, Xiaowei Chen, Peng Cao, Yu Fu, Zhihua Gao and 2 more

Abstract readReview
PubMed Publisher
In one paragraph

Review in Science China. Life sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed.

  1. Article
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  11. A neural pathway for social modulation of spontaneous locomotor activity (SoMo-SLA) inProceedings of the National Academy of Sciences of the United States of America · 2024
    Article
  12. Article
  13. Advances in neural circuits of innate fear defense behavior.Zhejiang da xue xue bao. Yi xue ban = Journal of Zhejiang University. Medical sciences · 2023
    Review
  14. Article
  15. Article
  16. Review
  17. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Wei Xiao *Department of Neurobiology and Department of Neurology of Second Affiliated Hospital, NHC and CAMS Key Laboratory of Medical Neurobiology, Zhejiang University School of Brain Science and Brain Medicine, Hangzhou, 310058, China.
Zhuo-Lei Jiao *Institute of Neuroscience, State Key Laboratory of Neuroscience, CAS Center for Excellence in Brain Science and Intelligence Technology, Shanghai Center for Brain Science and Brain-Inspired Intelligence Technology, Chinese Academy of Sciences, Shanghai, 200031, China.
Esra Senol *Institute of Molecular and Cell Biology, Agency for Science, Technology and Research (A*STAR), Singapore, 138667, Singapore.
Jiwei Yao *Center for Neurointelligence, School of Medicine, Chongqing University, Chongqing, 400030, China.
Miao Zhao *National Institute of Biological Sciences, Tsinghua Institute of Multidisciplinary Biomedical Research, Tsinghua University, Beijing, 100084, China.
Zheng-Dong Zhao *Boston Children's Hospital, Harvard Medical School, Boston, 02115, USA.
Xiaowei ChenBrain Research Center and State Key Laboratory of Trauma, Burns, and Combined Injury, Third Military Medical University, Chongqing, 400038, China. xiaowei_chen@tmmu.edu.cn.
Peng CaoNational Institute of Biological Sciences, Tsinghua Institute of Multidisciplinary Biomedical Research, Tsinghua University, Beijing, 100084, China. caopeng@nibs.ac.cn.
Yu FuInstitute of Molecular and Cell Biology, Agency for Science, Technology and Research (A*STAR), Singapore, 138667, Singapore. fu_yu@sbic.a-star.edu.sg.
Zhihua GaoDepartment of Neurobiology and Department of Neurology of Second Affiliated Hospital, NHC and CAMS Key Laboratory of Medical Neurobiology, Zhejiang University School of Brain Science and Brain Medicine, Hangzhou, 310058, China. zhihuagao@zju.edu.cn.
Wei L ShenSchool of Life Science and Technology, ShanghaiTech University, Shanghai, 201210, China. shenwei@shanghaitech.edu.cn.
Xiao-Hong XuInstitute of Neuroscience, State Key Laboratory of Neuroscience, CAS Center for Excellence in Brain Science and Intelligence Technology, Shanghai Center for Brain Science and Brain-Inspired Intelligence Technology, Chinese Academy of Sciences, Shanghai, 200031, China. xiaohong.xu@ion.ac.cn.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

All animals possess a plethora of innate behaviors that do not require extensive learning and are fundamental for their survival and propagation. With the advent of newly-developed techniques such as viral tracing and optogenetic and chemogenetic tools, recent studies are gradually unraveling neural circuits underlying different innate behaviors. Here, we summarize current development in our understanding of the neural circuits controlling predation, feeding, male-typical mating, and urination, highlighting the role of genetically defined neurons and their connections in sensory triggering, sensory to motor/motivation transformation, motor/motivation encoding during these different behaviors. Along the way, we discuss possible mechanisms underlying binge-eating disorder and the pro-social effects of the neuropeptide oxytocin, elucidating the clinical relevance of studying neural circuits underlying essential innate functions. Finally, we discuss some exciting brain structures recurrently appearing in the regulation of different behaviors, which suggests both divergence and convergence in the neural encoding of specific innate behaviors. Going forward, we emphasize the importance of multi-angle and cross-species dissections in delineating neural circuits that control innate behaviors.

Indexed as

Behavior, AnimalAnimalsBulimiaHypothalamusNeural PathwaysOxytocinPredatory BehaviorSexual Behavior, AnimalSocial BehaviorVisual PathwaysZona IncertaOxytocinfeedinginnate behaviorneural circuitsocial behaviorurination

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.