Evidence map›Paper›PMID 34985440›Full record

ArticleJournal of synchrotron radiation2022

Machine learning denoising of high-resolution X-ray nanotomography data.

Silja Flenner, Stefan Bruns, Elena Longo, Andrew J Parnell, Kilian E Stockhausen, Martin Müller, Imke Greving

Abstract read
In one paragraph

Article in Journal of synchrotron radiation, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. HoToPy: a toolbox for X-ray holo-tomography in Python.Journal of synchrotron radiation · 2025
    Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Dual-beam X-ray nano-holotomography.Journal of synchrotron radiation · 2024
    Article
  7. Article
  8. Article
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Silja FlennerHelmholtz-Zentrum Hereon, Max-Planck-Strasse 1, 21502 Geesthacht, Germany.
Stefan BrunsHelmholtz-Zentrum Hereon, Max-Planck-Strasse 1, 21502 Geesthacht, Germany.ORCID 0000-0003-1945-0549
Elena LongoHelmholtz-Zentrum Hereon, Max-Planck-Strasse 1, 21502 Geesthacht, Germany.ORCID 0000-0002-5035-7353
Andrew J ParnellDepartment of Physics and Astronomy, University of Sheffield, Western Bank, Sheffield S3 7RH, United Kingdom.
Kilian E StockhausenDepartment of Osteology and Biomechanics, University Medical Center, Lottestrasse 55a, 22529 Hamburg, Germany.ORCID 0000-0001-8923-8936
Martin MüllerHelmholtz-Zentrum Hereon, Max-Planck-Strasse 1, 21502 Geesthacht, Germany.
Imke GrevingHelmholtz-Zentrum Hereon, Max-Planck-Strasse 1, 21502 Geesthacht, Germany.

Funding

Deutsche Forschungsgemeinschaft 192346071
6 · The paper itself

Abstract

High-resolution X-ray nanotomography is a quantitative tool for investigating specimens from a wide range of research areas. However, the quality of the reconstructed tomogram is often obscured by noise and therefore not suitable for automatic segmentation. Filtering methods are often required for a detailed quantitative analysis. However, most filters induce blurring in the reconstructed tomograms. Here, machine learning (ML) techniques offer a powerful alternative to conventional filtering methods. In this article, we verify that a self-supervised denoising ML technique can be used in a very efficient way for eliminating noise from nanotomography data. The technique presented is applied to high-resolution nanotomography data and compared to conventional filters, such as a median filter and a nonlocal means filter, optimized for tomographic data sets. The ML approach proves to be a very powerful tool that outperforms conventional filters by eliminating noise without blurring relevant structural features, thus enabling efficient quantitative analysis in different scientific fields.

Indexed as

denoisingfull-field X-ray microscopymachine learningnanotomographyZernike phase contrast

Identifiers

PMID34985440
PMCPMC8733986

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.