Evidence map›Paper›PMID 34985334›Full record

ArticleMicrobiology spectrum2022

Destabilization of the Bacterial Interactome Identifies Nutrient Restriction-Induced Dysbiosis in Insect Guts.

Ramona Marasco, Marco Fusi, Matteo Callegari, Costanza Jucker, Francesca Mapelli, Sara Borin, Sara Savoldelli, Daniele Daffonchio, Elena Crotti

Open access · goldAbstract read
In one paragraph

Article in Microbiology spectrum, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
4.2field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 21 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 2 countries.

Ramona Marasco *Biological and Environmental Sciences and Engineering Division (BESE), Red Sea Research Center (RSRC), King Abdullah University of Science and Technologygrid.45672.32 (KAUST), Thuwal, Saudi Arabia.ORCID 0000-0003-4776-7519
Marco Fusi *Biological and Environmental Sciences and Engineering Division (BESE), Red Sea Research Center (RSRC), King Abdullah University of Science and Technologygrid.45672.32 (KAUST), Thuwal, Saudi Arabia.ORCID 0000-0001-7433-2487
Matteo Callegari *Biological and Environmental Sciences and Engineering Division (BESE), Red Sea Research Center (RSRC), King Abdullah University of Science and Technologygrid.45672.32 (KAUST), Thuwal, Saudi Arabia.
Costanza JuckerDepartment of Food, Environmental and Nutritional Sciences (DeFENS), University of Milangrid.4708.b, Milan, Italy.
Francesca MapelliDepartment of Food, Environmental and Nutritional Sciences (DeFENS), University of Milangrid.4708.b, Milan, Italy.
Sara BorinDepartment of Food, Environmental and Nutritional Sciences (DeFENS), University of Milangrid.4708.b, Milan, Italy.
Sara SavoldelliDepartment of Food, Environmental and Nutritional Sciences (DeFENS), University of Milangrid.4708.b, Milan, Italy.
Daniele DaffonchioBiological and Environmental Sciences and Engineering Division (BESE), Red Sea Research Center (RSRC), King Abdullah University of Science and Technologygrid.45672.32 (KAUST), Thuwal, Saudi Arabia.
Elena CrottiDepartment of Food, Environmental and Nutritional Sciences (DeFENS), University of Milangrid.4708.b, Milan, Italy.
University of Milan · ITKing Abdullah University of Science and Technology · SA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Stress-associated dysbiosis of microbiome can have several configurations that, under an energy landscape conceptual framework, can change from one configuration to another due to different alternating selective forces. It has been proposed-according to the Anna Karenina Principle-that in stressed individuals the microbiome are more dispersed (i.e., with a higher within-beta diversity), evidencing the grade of dispersion as indicator of microbiome dysbiosis. We hypothesize that although dysbiosis leads to different microbial communities in terms of beta diversity, these are not necessarily differently dispersed (within-beta diversity), but they form disrupted networks that make them less resilient to stress. To test our hypothesis, we select nutrient restriction (NR) stress that impairs host fitness but does not introduce overt microbiome selectors, such as toxic compounds and pathogens. We fed the polyphagous black soldier fly,

Indexed as

Gastrointestinal MicrobiomeAnimal FeedAnimalsBacteriaBiodiversityNutrientsSimuliidaeNutrientsbacterial microbiomebeta-diversityblack soldier flyco-occurrence networkdispersiondysbiosisgutinteractomekeystone speciesnutrient restriction

Identifiers

PMID34985334
PMCPMC8729773
OpenAlexW4205560239

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.