Evidence map›Paper›PMID 34985120›Full record

SynthesisCardiology journal

Impact of COVID-19 on in-hospital cardiac arrest outcomes: An updated meta-analysis.

Karol Bielski, Katarzyna Makowska, Adam Makowski, Tomasz Kopiec, Aleksandra Gasecka, Mariola Malecka, Michal Pruc, Zubaid Rafique, Frank W Peacock, Andrea Denegri and 1 more

Abstract readMeta-Analysis
In one paragraph

Synthesis in Cardiology journal. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Review
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

11 authors.

Karol BielskiResearch Unit, Polonia University, Czestochowa, Poland.ORCID 0000-0002-2428-0671
Katarzyna MakowskaFirst Chair and Department of Cardiology, Medical University of Warsaw, Poland.
Adam MakowskiFirst Chair and Department of Cardiology, Medical University of Warsaw, Poland.
Tomasz KopiecFirst Chair and Department of Cardiology, Medical University of Warsaw, Poland.
Aleksandra GaseckaFirst Chair and Department of Cardiology, Medical University of Warsaw, Poland.ORCID 0000-0001-5083-7587
Mariola MaleckaInstitute of Outcomes Research, Maria Sklodowska-Curie Medical Academy, Warsaw, Poland.
Michal PrucResearch Unit, Polish Society of Disaster Medicine, Warsaw, Poland.ORCID 0000-0002-2140-9732
Zubaid RafiqueHenry JN Taub Department of Emergency Medicine, Baylor College of Medicine, Houston, TX, United States.ORCID 0000-0002-4176-5988
Frank W PeacockHenry JN Taub Department of Emergency Medicine, Baylor College of Medicine, Houston, TX, United States.
Andrea DenegriCardiology Division, Department of Biomedical, Metabolic and Neural Sciences, University of Modena and Reggio Emilia, Policlinico di Modena, Modena, Italy.ORCID 0000-0001-5283-3176
Lukasz SzarpakResearch Unit, Polish Society of Disaster Medicine, Warsaw, Poland. lukasz.szarpak@gmail.com.ORCID 0000-0002-0973-5455

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe main purposes of this meta-analysis are to update the information about the impact of coronavirus disease 2019 (COVID-19) pandemic on outcomes of in-hospital cardiac arrest (IHCA) and to investigate the impact of being infected by by severe acute respiratory syndrome coronavirus type 2 (SARS-CoV-2) on IHCA outcomes.

methodsThe current meta-analysis is an update and follows the recommendations of Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA).

resultsIn analyses, pre- and intra-COVID-19 periods were observed for: shockable rhythms in 17.6% vs. 16.2% (odds ratio [OR]: 1.11; 95% confidence interval [CI]: 0.71-1.72; p = 0.65), return of spontaneous circulation (ROSC) in 47.4% vs. 44.0% (OR: 1.36; 95% CI: 0.90-2.07; p = 0.15), 30-day mortality in 59.8% vs. 60.9% (OR: 0.95; 95% CI: 0.75-1.22; p = 0.69) and overall mortality 75.8% vs. 74.7% (OR: 0.80; 95% CI: 0.49-1.28; p = 0.35), respectively. In analyses, SARS-CoV-2 positive and negative patients were observed for: shockable rhythms in 9.6% vs. 19.8% (OR: 0.51; 95% CI: 0.35-0.73; p < 0.001), ROSC in 33.9% vs. 52.1% (OR: 0.47; 95% CI: 0.30-0.73; p < 0.001), 30-day mortality in 77.2% vs. 59.7% (OR: 2.08; 95% CI: 1.28-3.38; p = 0.003) and overall mortality in 94.9% vs. 76.7% (OR: 3.20; 95% CI: 0.98-10.49; p = 0.05), respectively.

conclusionsDespite ROSC, 30-day and overall mortality rate were not statistically different in pre- vs. intra-COVID-19 periods, a lower incidence of ROSC and higher 20-day mortality rate were observed in SARS-CoV-2 (+) compared to SARS-CoV-2 (-) patients.

Indexed as

Cardiopulmonary ResuscitationCOVID-19Heart ArrestHospitalsHumansSARS-CoV-2cardiopulmonary resuscitationcoronavirus disease 2019COVID-19in-hospital cardiac arrestmeta-analysisoutcomepandemicSARS-CoV-2

Identifiers

PMID34985120
PMCPMC8747824

What OpenQuestion holds

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LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.