Evidence map›Paper›PMID 34984929›Full record

ArticleAmerican journal of physiology. Gastrointestinal and liver physiology2022

Exposure to binge ethanol and fatty acid ethyl esters exacerbates chronic ethanol-induced pancreatic injury in hepatic alcohol dehydrogenase-deficient deer mice.

Mukund P Srinivasan, Kamlesh K Bhopale, Anna A Caracheo, Lata Kaphalia, Bin Gong, Vsevolod L Popov, Paul J Boor, G A Shakeel Ansari, Bhupendra S Kaphalia

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in American journal of physiology. Gastrointestinal and liver physiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
2.2field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Article
  6. Review
  7. Protective Effects and Mechanism ofInternational journal of molecular sciences · 2024
    Article
  8. Fatty Acid Ethyl Ethers: New Modulators of Acute Ethanol-Mediated Hepatotoxicity?Cellular and molecular gastroenterology and hepatology · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Mukund P SrinivasanDepartment of Pathology, The University of Texas Medical Branch, Galveston, Texas.ORCID 0000-0002-3307-2305
Kamlesh K BhopaleDepartment of Pathology, The University of Texas Medical Branch, Galveston, Texas.
Anna A CaracheoDepartment of Pathology, The University of Texas Medical Branch, Galveston, Texas.
Lata KaphaliaDepartment of Internal Medicine, The University of Texas Medical Branch, Galveston, Texas.
Bin GongDepartment of Pathology, The University of Texas Medical Branch, Galveston, Texas.
Vsevolod L PopovDepartment of Pathology, The University of Texas Medical Branch, Galveston, Texas.
Paul J BoorDepartment of Pathology, The University of Texas Medical Branch, Galveston, Texas.
G A Shakeel AnsariDepartment of Pathology, The University of Texas Medical Branch, Galveston, Texas.
Bhupendra S KaphaliaDepartment of Pathology, The University of Texas Medical Branch, Galveston, Texas.ORCID 0000-0002-3794-0392
The University of Texas Medical Branch at Galveston · US

Funding

Role of Alcohol Metabolism in Alcoholic Chronic PancreatitisR01AA025850 · NIAAA · UNIVERSITY OF TEXAS MED BR GALVESTON · PI KAPHALIA, BHUPENDRA S · 2017 to 2021
$1.7M
AMPK Signaling and Chronic Alcoholic PancreatitisR21AA024699 · NIAAA · UNIVERSITY OF TEXAS MED BR GALVESTON · PI KAPHALIA, BHUPENDRA S · 2016 to 2017
$407k
NIAAA NIH HHS R01 AA025850NIAAA NIH HHS R21 AA024699
6 · The paper itself

Abstract

Alcoholic chronic pancreatitis (ACP) is a fibroinflammatory disease of the pancreas. However, metabolic basis of ACP is not clearly understood. In this study, we evaluated differential pancreatic injury in hepatic alcohol dehydrogenase-deficient (ADH

Indexed as

Alcohol DehydrogenasePancreatitis, AlcoholicAnimalsBlood Alcohol ContentEstersEthanolFatty AcidsPeromyscusAlcohol DehydrogenaseBlood Alcohol ContentEstersEthanolFatty Acidsalcoholchronic pancreatitisdeer miceER/oxidative stressfatty acid ethyl esters

Identifiers

PMID34984929
PMCPMC8816639
OpenAlexW4206267734

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.