Evidence map›Paper›PMID 34984851›Full record

Trial reportClinical pharmacology in drug development2022

Pharmacokinetic Drug Interaction Between Raloxifene and Cholecalciferol in Healthy Volunteers.

Hae Won Lee, Woo Youl Kang, Wookjae Jung, Mi-Ri Gwon, Kyunghee Cho, Backhwan Lee, Sook Jin Seong, Young-Ran Yoon

Open access · hybridAbstract readClinical Trial, Phase IRandomized Controlled Trial
In one paragraph

Trial report in Clinical pharmacology in drug development, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.6field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 2 countries.

Hae Won LeeDepartment of Molecular Medicine, School of Medicine, Kyungpook National University, Daegu, Republic of Korea.
Woo Youl KangDepartment of Molecular Medicine, School of Medicine, Kyungpook National University, Daegu, Republic of Korea.
Wookjae JungDepartment of Molecular Medicine, School of Medicine, Kyungpook National University, Daegu, Republic of Korea.
Mi-Ri GwonDepartment of Molecular Medicine, School of Medicine, Kyungpook National University, Daegu, Republic of Korea.
Kyunghee ChoAnalytical Research Division, Biocore Co. Ltd., Seoul, Republic of Korea.
Backhwan LeeDepartment of Clinical Development, Alvogen Korea Co. Ltd., Seoul, Republic of Korea.
Sook Jin SeongDepartment of Molecular Medicine, School of Medicine, Kyungpook National University, Daegu, Republic of Korea.
Young-Ran YoonDepartment of Molecular Medicine, School of Medicine, Kyungpook National University, Daegu, Republic of Korea.
Kyungpook National University Hospital · KRKyungpook National University · KRAlvogen (South Korea) · KRAnalytical Services · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Osteoporosis is a common skeletal disorder, often leading to fragility fracture. Combination therapy with raloxifene, a selective estrogen receptor modulator, and cholecalciferol (vitamin D

Indexed as

CholecalciferolRaloxifene HydrochlorideAdultCross-Over StudiesDrug InteractionsHealthy VolunteersHumansMaleCholecalciferolRaloxifene Hydrochloridecholecalciferoldrug-drug interactionosteoporosispharmacokineticsraloxifene

Identifiers

PMID34984851
PMCPMC9305550
OpenAlexW4206334172

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.