Evidence map›Paper›PMID 34984664›Full record

ReviewDrug delivery and translational research2022

Recent progress of macrophage vesicle-based drug delivery systems.

Wen-Jie Xu, Jia-Xin Cai, Yong-Jiang Li, Jun-Yong Wu, Daxiong Xiang

Abstract readReview
PubMed Publisher
In one paragraph

Review in Drug delivery and translational research, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

  1. Review
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  9. Progress of nanomaterials in the treatment of thrombus.Drug delivery and translational research · 2024
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  11. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Wen-Jie XuDepartment of Pharmacy, The Second Xiangya Hospital, Central South University, Changsha, 410011, Hunan, China.
Jia-Xin CaiDepartment of Pharmacy, The Second Xiangya Hospital, Central South University, Changsha, 410011, Hunan, China.
Yong-Jiang LiDepartment of Pharmacy, The Second Xiangya Hospital, Central South University, Changsha, 410011, Hunan, China.
Jun-Yong WuDepartment of Pharmacy, The Second Xiangya Hospital, Central South University, Changsha, 410011, Hunan, China.
Daxiong XiangDepartment of Pharmacy, The Second Xiangya Hospital, Central South University, Changsha, 410011, Hunan, China. xiangdaxiong@csu.edu.cn.ORCID 0000-0002-4226-6574

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Nanoparticle drug delivery systems (NDDSs) are promising platforms for efficient delivery of drugs. In the past decades, many nanomedicines have received clinical approval and completed translation. With the rapid advance of nanobiotechnology, natural vectors are emerging as novel strategies to carry and delivery nanoparticles and drugs for biomedical applications. Among diverse types of cells, macrophage is of great interest for their essential roles in inflammatory and immune responses. Macrophage-derived vesicles (MVs), including exosomes, microvesicles, and those from reconstructed membranes, may inherit the chemotactic migration ability and high biocompatibility. The unique properties of MVs make them competing candidates as novel drug delivery systems for precision nanomedicine. In this review, the advantages and disadvantages of existing NDDSs and MV-based drug delivery systems (MVDDSs) were compared. Then, we summarized the potential applications of MVDDSs and discuss future perspectives. The development of MVDDS may provide avenues for the treatment of diseases involving an inflammatory process.

Indexed as

Cell-Derived MicroparticlesNanoparticlesDrug Delivery SystemsMacrophagesNanomedicineApplicationDrug delivery systemMacrophageVesicle

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.