Evidence map›Paper›PMID 34984646›Full record

ArticleInfection2022

COVID-19: vaccination vs. hospitalization.

Oguz Uzun, Tekin Akpolat, Ayhan Varol, Sema Turan, Serife Gokbulut Bektas, Pelin Duru Cetinkaya, Mazlum Dursun, Nurten Bakan, Burcu Baran Ketencioglu, Murat Bayrak and 45 more

Abstract readMulticenter Study
In one paragraph

Article in Infection, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed.

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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

55 authors.

Oguz UzunDepartment of Pulmonary Medicine, Faculty of Medicine, Ondokuz Mayis University, Samsun, Turkey. oguzuzun67@yahoo.com.tr.ORCID http://orcid.org/0000-0002-0475-4198
Tekin AkpolatDepartment of Internal Medicine and Nephrology, Faculty of Medicine, Istinye University, Istanbul, Turkey.
Ayhan VarolKepez State Hospital, Antalya, Turkey.
Sema TuranDepartment of Intensive Care Unit, Ankara City Hospital, Ankara, Turkey.
Serife Gokbulut BektasDepartment of Intensive Care Unit, Ankara City Hospital, Ankara, Turkey.
Pelin Duru CetinkayaAdana City Hospital, Adana, Turkey.
Mazlum DursunSiirt Training and Research Hospital, Siirt, Turkey.
Nurten BakanŞehit Prof Dr İlhan Varank Training and Research Hospital, İstanbul, Turkey.
Burcu Baran KetenciogluDepartment of Pulmonary Disease, School of Medicine, Erciyes University, Kayseri, Turkey.
Murat BayrakKepez State Hospital, Antalya, Turkey.
Serap Argun BarisDepartment of Pulmonary Disease, School of Medicine, Kocaeli University, Kocaeli, Turkey.
Rahmet GunerDepartment of Infectious Diseases and Clinical Microbiology, Ankara City Hospital, Yildirim Beyazit University, Ankara, Turkey.
Ozgur GunalDepartment of Infectious Diseases and Clinical Microbiology, Samsun Training and Research Hospital, University of Medical Science, Samsun, Turkey.
Serkan NuralDepartment of Pulmonary Medicine, Training and Research Hospital, Hatay, İstanbul, Turkey.
Pelin Pinar DenizCity Hospital, Adana, Turkey.
Oya Baydar ToprakDepartment of Pulmonary Medicine, Faculty of Medicine, Cukuroca University, Adana, Turkey.
Gulcihan OzkanMaslak Acibadem Hospital, Operating Room Services Department and Private Acıbadem Maslak Hospital, Vocational School, Nişantaşı University, İstanbul, Turkey.
Ayça GumusKepez State Hospital, Antalya, Turkey.
Ferhan KergetDepartment of Infection Diseases and Clinical Microbiology, Faculty of Medicine, Erzurum Regional Education and Research Hospital, Health Sciences University, Erzurum, Turkey.
Merve ErcelikDinar State Hospital, Afyon, Turkey.
Ozlem AtaogluDuzce Ataturk State Hospital, Duzce, Turkey.
Aycan YukselDepartment of Pulmonary Medicine, Faculty of Medicine, Ufuk University, Ankara, Turkey.
Gungor AtesGenesis Private Hospital, Diyarbakır, Turkey.
Oya Eren KutsoyluDepartment of Infectious Diseases and Clinical Microbiology, Faculty of Medicine, Dokuz Eylül University, İzmir, Turkey.
Neslihan KoseBilecik State Hospital, Bilecik, Turkey.
Deniz KizilirmakDepartment of Pulmonary Medicine, Faculty of Medicine, Celal Bayar University, Manisa, Turkey.
Serdar KeskinSiirt Training and Research Hospital, Siirt, Turkey.
Okkes GultekinOltu State Hospital, Erzurum, Turkey.
Nilüfer CoskunŞehit Prof Dr İlhan Varank Training and Research Hospital, İstanbul, Turkey.
Emine Serap YilmazDepartment of Pulmonary Medicine, Medical Faculty, Training and Research Hospital, Ordu University, Ordu, Turkey.
Selen UsluDepartment of Pulmonary Medicine, Medical Faculty, Training and Research Hospital, Ordu University, Ordu, Turkey.
İlknur BasyigitDepartment of Pulmonary Disease, School of Medicine, Kocaeli University, Kocaeli, Turkey.
Begüm ErganDivision of Intensive Care, Department of Pulmonary and Critical Care, Faculty of Medicine, Dokuz Eylül University, Izmir, Turkey.
Figen DeveciDepartment of Pulmonary Medicine, Faculty of Medicine, Firat University, Elazıg, Turkey.
Mehmet Nuri YakarDivision of Intensive Care, Department of Anaesthesiology and Reanimation, Faculty of Medicine, Dokuz Eylül University, Izmir, Turkey.
Cigdem ZuhurPrivate Gelisim Hospital, İskenderun, Turkey.
Gulseren SagcanPrivate Altunizade Maslak Hospital, İstanbul, Turkey.
Zeynep Ture YuceDepartment of Infectious Diseases and Clinical Microbiology, Erciyes University, Kayseri, Turkey.
Mutlu KuluozturkDepartment of Pulmonary Medicine, Faculty of Medicine, Firat University, Elazıg, Turkey.
Mehmet Emin SezginSiirt Training and Research Hospital, Siirt, Turkey.
Esma Nur Aktepe SezginSiirt Training and Research Hospital, Siirt, Turkey.
Yavuz HavlucuDepartment of Pulmonary Medicine, Faculty of Medicine, Celal Bayar University, Manisa, Turkey.
Caglar CuhadarogluPrivate Altunizade Maslak Hospital, İstanbul, Turkey.
Oguz KilincDepartment of Pulmonary Medicine, Faculty of Medicine, Dokuz Eylül University, İzmir, Turkey.
Hasim BoyaciDepartment of Pulmonary Disease, School of Medicine, Kocaeli University, Kocaeli, Turkey.
Hayriye AltunaySiirt Training and Research Hospital, Siirt, Turkey.
Mehmet AktiSiirt Training and Research Hospital, Siirt, Turkey.
Zehra Bastepe DursunDepartment of Infectious Diseases and Clinical Microbiology, Kayseri City Hospital, Health Science University, Kayseri, Turkey.
Ayse Kaya KalemDepartment of Infectious Diseases and Clinical Microbiology, Ankara City Hospital, Yildirim Beyazit University, Ankara, Turkey.
Sinem Akkaya IsikSultan Abdülhamid Han Training and Research Hospital, İstanbul, Turkey.
Levent AkyildizPrivate Memorial Hospital, Diyarbakır, Turkey.
Nilüfer AykacAcademic Hospital, İstanbul, Turkey.
Mehmet Selim AlmazPrivate Memorial Hospital, Diyarbakır, Turkey.
Nurdan KokturkDepartment of Pulmonary Medicine, Faculty of Medicine, Gazi University, Ankara, Turkey.
Oya ItilDepartment of Pulmonary Medicine, Faculty of Medicine, Dokuz Eylul University, İzmir, Turkey.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveVaccination is the most efficient way to control the coronavirus disease 2019 (COVID-19) pandemic, but vaccination rates remain below the target level in most countries. This multicenter study aimed to evaluate the vaccination status of hospitalized patients and compare two different booster vaccine protocols.

settingInoculation in Turkey began in mid-January 2021. Sinovac was the only available vaccine until April 2021, when BioNTech was added. At the beginning of July 2021, the government offered a third booster dose to healthcare workers and people aged > 50 years who had received the two doses of Sinovac. Of the participants who received a booster, most chose BioNTech as the third dose.

methodsWe collected data from 25 hospitals in 16 cities. Patients hospitalized between August 1 and 10, 2021, were included and categorized into eight groups according to their vaccination status.

resultsWe identified 1401 patients, of which 529 (37.7%) were admitted to intensive care units. Nearly half (47.8%) of the patients were not vaccinated, and those with two doses of Sinovac formed the second largest group (32.9%). Hospitalizations were lower in the group which received 2 doses of Sinovac and a booster dose of BioNTech than in the group which received 3 doses of Sinovac.

conclusionEffective vaccinations decreased COVID-19-related hospitalizations. The efficacy after two doses of Sinovac may decrease over time; however, it may be enhanced by adding a booster dose. Moreover, unvaccinated patients may be persuaded to undergo vaccination.

Indexed as

COVID-19VaccinesCOVID-19 VaccinesHospitalizationHumansSARS-CoV-2VaccinationCOVID-19 VaccinesVaccinesBioNTechCOVID-19 pandemicCOVID-19 vaccineSinoVac

Identifiers

PMID34984646
PMCPMC8725959

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.