Evidence map›Paper›PMID 34984597›Full record

ArticleJournal of assisted reproduction and genetics2022

Long-term storage of gametes and gonadal tissues at room temperatures: the end of the ice age?

Pierre Comizzoli, Pasqualino Loi, Pasquale Patrizio, Allison Hubel

Open access · greenAbstract read
In one paragraph

Article in Journal of assisted reproduction and genetics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.4field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 7 citations in OpenAlex.

  1. Review
  2. Review
  3. Designed Multifunctional Peptides for Intracellular Targets.Antibiotics (Basel, Switzerland) · 2022
    Review
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 4 institutions in 2 countries.

Pierre ComizzoliSmithsonian Conservation Biology Institute, National Zoological Park, Washington, DC, USA. comizzolip@si.edu.ORCID http://orcid.org/0000-0003-3079-9063
Pasqualino LoiFaculty of Veterinary Medicine, University of Teramo, Teramo, Italy.ORCID http://orcid.org/0000-0003-4631-7663
Pasquale PatrizioMiller School of Medicine, University of Miami, Miami, FL, USA.ORCID http://orcid.org/0000-0003-4796-7078
Allison HubelDepartment of Mechanical Engineering, University of Minnesota, Minneapolis, MN, USA.ORCID http://orcid.org/0000-0001-5856-0500
Smithsonian Conservation Biology Institute · USUniversity of Miami · USUniversity of Minnesota · USUniversity of Teramo · IT

Funding

Drying, Storing, and Reanimating Egg Germinal Vesicles to Preserve FertilityR01OD023139 · OD · SMITHSONIAN INSTITUTION · PI COMIZZOLI, PIERRE · 2017 to 2021
$2.2M
NIH HHS R01 OD023139
6 · The paper itself

Abstract

Long-term preservation of viable spermatozoa, eggs, embryos, and gonadal tissues of good quality is essential in human reproductive medicine and for the population management of livestock, laboratory, and wild species. Instead of using freezing temperatures, encouraging findings indicate that structures and functions of gametes or gonadal tissues can be suspended in trehalose glass after dehydration and then preserved at supra-zero temperatures. As a new era in fertility preservation and biobanking is about to start, the advantages, needs, and implications of germplasm storage at room temperatures must be carefully examined. Although very promising, the development of alternate biobanking strategies does not necessarily mean that the end of the "ice age" (cryopreservation) is near.

Indexed as

Biological Specimen BanksFertility PreservationCryopreservationGerm CellsHumansMaleSpermatozoaTemperatureAnhydrobiosisBiobankingCryopreservationFreezing temperaturesRoom temperature storage

Identifiers

PMID34984597
PMCPMC8956754
OpenAlexW4206568342

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.