Evidence map›Paper›PMID 34984574›Full record

ArticleEmergency radiology2022

Deep learning versus iterative image reconstruction algorithm for head CT in trauma.

Zlatan Alagic, Jacqueline Diaz Cardenas, Kolbeinn Halldorsson, Vitali Grozman, Stig Wallgren, Chikako Suzuki, Johan Helmenkamp, Seppo K Koskinen

Open access · hybridAbstract read
In one paragraph

Article in Emergency radiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed, 1 pooled it
5.3field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 1 synthesis or guideline pooled it, 40 citations in OpenAlex.

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  13. Deep learning-based reconstruction improves image quality in low-dose head CT angiography.Malawi medical journal : the journal of Medical Association of Malawi · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Zlatan AlagicDepartment of Diagnostic Radiology, Karolinska University Hospital, 171 76, Stockholm, Sweden. zlatan.alagic@regionstockholm.se.
Jacqueline Diaz CardenasDepartment of Diagnostic Radiology, Karolinska University Hospital, 171 76, Stockholm, Sweden.
Kolbeinn HalldorssonDepartment of Diagnostic Radiology, Karolinska University Hospital, 171 76, Stockholm, Sweden.
Vitali GrozmanDepartment of Diagnostic Radiology, Karolinska University Hospital, 171 76, Stockholm, Sweden.
Stig WallgrenDepartment of Diagnostic Radiology, Karolinska University Hospital, 171 76, Stockholm, Sweden.
Chikako SuzukiDepartment of Molecular Medicine and Surgery, Karolinska Institutet, 17177, Stockholm, Sweden.
Johan HelmenkampDepartment of Medical Physics and Nuclear Medicine, Karolinska University Hospital, 17176, Stockholm, Sweden.
Seppo K KoskinenDepartment of Diagnostic Radiology, Karolinska University Hospital, 171 76, Stockholm, Sweden.
Karolinska University Hospital · SEKarolinska Institutet · SE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo compare the image quality between a deep learning-based image reconstruction algorithm (DLIR) and an adaptive statistical iterative reconstruction algorithm (ASiR-V) in noncontrast trauma head CT.

methodsHead CT scans from 94 consecutive trauma patients were included. Images were reconstructed with ASiR-V 50% and the DLIR strengths: low (DLIR-L), medium (DLIR-M), and high (DLIR-H). The image quality was assessed quantitatively and qualitatively and compared between the different reconstruction algorithms. Inter-reader agreement was assessed by weighted kappa.

resultsDLIR-M and DLIR-H demonstrated lower image noise (p < 0.001 for all pairwise comparisons), higher SNR of up to 82.9% (p < 0.001), and higher CNR of up to 53.3% (p < 0.001) compared to ASiR-V. DLIR-H outperformed other DLIR strengths (p ranging from < 0.001 to 0.016). DLIR-M outperformed DLIR-L (p < 0.001) and ASiR-V (p < 0.001). The distribution of reader scores for DLIR-M and DLIR-H shifted towards higher scores compared to DLIR-L and ASiR-V. There was a tendency towards higher scores with increasing DLIR strengths. There were fewer non-diagnostic CT series for DLIR-M and DLIR-H compared to ASiR-V and DLIR-L. No images were graded as non-diagnostic for DLIR-H regarding intracranial hemorrhage. The inter-reader agreement was fair-good between the second most and the less experienced reader, poor-moderate between the most and the less experienced reader, and poor-fair between the most and the second most experienced reader.

conclusionThe image quality of trauma head CT series reconstructed with DLIR outperformed those reconstructed with ASiR-V. In particular, DLIR-M and DLIR-H demonstrated significantly improved image quality and fewer non-diagnostic images. The improvement in qualitative image quality was greater for the second most and the less experienced readers compared to the most experienced reader.

Indexed as

Deep LearningAlgorithmsHumansImage Processing, Computer-AssistedRadiation DosageRadiographic Image Interpretation, Computer-AssistedTomography, X-Ray ComputedAdaptive statistical iterative reconstruction-VeoDeep learning image reconstructionHead CTImage qualityTrauma

Identifiers

PMID34984574
PMCPMC8917108
OpenAlexW4206294835

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.