Evidence map›Paper›PMID 34984300›Full record

ArticleACS omega2021

Phenotype Screening of an Azole-bisindole Chemical Library Identifies URB1483 as a New Antileishmanial Agent Devoid of Toxicity on Human Cells.

Aurora Diotallevi, Laura Scalvini, Gloria Buffi, Yolanda Pérez-Pertejo, Mauro De Santi, Michele Verboni, Gianfranco Favi, Mauro Magnani, Alessio Lodola, Simone Lucarini and 1 more

Abstract read
In one paragraph

Article in ACS omega, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
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  7. Review
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Aurora DiotalleviDepartment of Biomolecular Sciences, University of Urbino Carlo Bo, 61029 Urbino (PU), Italy.ORCID https://orcid.org/0000-0001-5456-1821
Laura ScalviniDepartment of Food and Drug, University of Parma, 43124 Parma, Italy.ORCID https://orcid.org/0000-0003-3610-527X
Gloria BuffiDepartment of Biomolecular Sciences, University of Urbino Carlo Bo, 61029 Urbino (PU), Italy.ORCID https://orcid.org/0000-0001-6288-8787
Yolanda Pérez-PertejoDepartment of Biomedical Sciences, University of León, 24071 León, Spain.
Mauro De SantiDepartment of Biomolecular Sciences, University of Urbino Carlo Bo, 61029 Urbino (PU), Italy.
Michele VerboniDepartment of Biomolecular Sciences, University of Urbino Carlo Bo, 61029 Urbino (PU), Italy.ORCID https://orcid.org/0000-0001-5648-521X
Gianfranco FaviDepartment of Biomolecular Sciences, University of Urbino Carlo Bo, 61029 Urbino (PU), Italy.ORCID https://orcid.org/0000-0003-3112-819X
Mauro MagnaniDepartment of Biomolecular Sciences, University of Urbino Carlo Bo, 61029 Urbino (PU), Italy.
Alessio LodolaDepartment of Food and Drug, University of Parma, 43124 Parma, Italy.ORCID https://orcid.org/0000-0002-8675-1002
Simone LucariniDepartment of Biomolecular Sciences, University of Urbino Carlo Bo, 61029 Urbino (PU), Italy.ORCID https://orcid.org/0000-0002-3667-1207
Luca GalluzziDepartment of Biomolecular Sciences, University of Urbino Carlo Bo, 61029 Urbino (PU), Italy.ORCID https://orcid.org/0000-0002-1747-526X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We report the evaluation of a small library of azole-bisindoles for their antileishmanial potential, in terms of efficacy on

Identifiers

PMID34984300
PMCPMC8717589

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.