Evidence map›Paper›PMID 34984152›Full record

ReviewCureus2021

Celiac Disease, Beyond the Bowel: A Review of Its Neurological Manifestations.

Saawan C Patel, Devarashetty Shreya, Diana I Zamora, Gautami S Patel, Idan Grossmann, Kevin Rodriguez, Mridul Soni, Pranay K Joshi, Ibrahim Sange

Open access · diamondAbstract readReview
In one paragraph

Review in Cureus, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.0field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 7 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 6 institutions in 5 countries.

Saawan C PatelInternal Medicine, Pramukhswami Medical College, Karamsad, IND.
Devarashetty ShreyaInternal Medicine, Gandhi Medical College, Secunderabad, Hyderabad, IND.
Diana I ZamoraGeneral Medicine, Universidad de Ciencias Médicas Andrés Vesalio Guzman, San José, CRI.
Gautami S PatelInternal Medicine, Pramukhswami Medical College, Karamsad, IND.
Idan GrossmannResearch, Medical University of Silesia in Katowice Faculty of Medical Sciences, Katowice, POL.
Kevin RodriguezResearch, Universidad Americana (UAM) Facultad de Medicina, Managua, NIC.
Mridul SoniResearch, Shri Lal Bahadur Shastri Government Medical College, Mandi, IND.
Pranay K JoshiDepartment of Medicine, Byramjee Jeejabhoy Medical College, Ahmedabad, IND.
Ibrahim SangeResearch, Karamshi Jethabhai Somaiya Medical College, Mumbai, IND.
Medical University of Silesia · PLPramukhswami Medical College · INUniversidad American College · NIB.J. Medical College · INGovernment Medical College · INK J Somaiya Medical College · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Celiac disease (CD) is a multi-systemic autoimmune condition that causes a hyperinflammatory response when gluten is ingested. There has been a shift in the clinical presentation of CD from a mere malabsorption disorder to an autoimmune condition that affects multiple organ systems, which could increase the rate of hospitalizations and a decreased quality of life. This article has compiled various studies that have explored the neurological manifestations of celiac disease, their epidemiology, possible pathogenic mechanisms, diagnosis, and treatment. The most common neurological conditions include gluten ataxia (GA), gluten neuropathy, gluten encephalopathy, and epilepsy which usually present as sporadic diseases which are difficult to diagnose in the absence of gastrointestinal (GI) symptoms. The treatment for most of these conditions is a gluten-free diet (GFD) regardless of GI involvement.

Indexed as

extra-intestinal manifestations of celiac diseasegluten ataxiagluten encephalopathygluten intolerancegluten neuropathygluten-related neuropathologyneurological features of celiac disease

Identifiers

PMID34984152
PMCPMC8720288
OpenAlexW3214849118

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.