Evidence map›Paper›PMID 34984146›Full record

ArticleCureus2021

Hormone Receptor Down-Regulation in Metastatic Breast Cancer After Endocrine Therapy Detected in Oophorectomy: A Case Report and Review of Literature.

Marina Barron, Amira Asaad, Philip Idaewor, Noreen Rasheed, Abdalla Saad Abdalla Al-Zawi

Open access · diamondAbstract readCase Reports
In one paragraph

Article in Cureus, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 4 institutions in 2 countries.

Marina BarronEmergency Department, South West Acute Hospital, Enniskillen, GBR.
Amira AsaadSurgery, University College Hospital, London, GBR.
Philip IdaeworHistopathology/Cellular Pathology, Mid and South Essex NHS Foundation Trust, Basildon, GBR.
Noreen RasheedRadiology, Basildon and Thurrock University Hospitals NHS Foundation Trust, Basildon, GBR.
Abdalla Saad Abdalla Al-ZawiGeneral and Breast Surgery, Mid and South Essex NHS Foundation Trust, Basildon, GBR.
South Essex Partnership University Foundation NHS Trust · GBAnglia Ruskin University · GBBasildon Hospital · GBUniversity College London · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Globally, breast cancer is the most frequently diagnosed malignancy among women; it is also one of the leading causes of cancer mortality among females. The most common sites for metastases are the lungs, bones, liver, and brain. Breast cancer is recognized as one of the most common primary sites of metastatic lesions in the ovaries and is often associated with multiple extra-ovarian metastases. Here, we report a case of occult breast cancer metastases to the ovaries with a down-regulated hormonal immunohistochemistry profile after endocrine therapy, encountered incidentally after oophorectomy.

Indexed as

aromatase inhibitorbreast lobular carcinomaestrogen receptoroophorectomyovarian metastasisprogesteronetamoxifen

Identifiers

PMID34984146
PMCPMC8715835
OpenAlexW3216570310

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.