Evidence map›Paper›PMID 34984131›Full record

ReviewCureus2021

Unexplained Anemia in the Elderly.

Jose C Alvarez-Payares, Sebastián Rivera-Arismendy, Pablo Ruiz-Bravo, Sara M Sánchez-Salazar, Rene A Manzur, Sara I Ramirez-Urrea, Andres Puello

Open access · diamondAbstract readReview
In one paragraph

Review in Cureus, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.0field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. The Role of Inflammation in Age-Associated Changes in Red Blood System.International journal of molecular sciences · 2023
    Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 1 country.

Jose C Alvarez-PayaresInternal Medicine, University of Antioquia, Medellín, COL.
Sebastián Rivera-ArismendyInternal Medicine, University of Antioquia, Medellín, COL.
Pablo Ruiz-BravoInternal Medicine, University of Antioquía, Medellín, COL.
Sara M Sánchez-SalazarInternal Medicine, University of Antioquía, Medellín, COL.
Rene A ManzurInternal Medicine, University of Antioquia, Medellín, COL.
Sara I Ramirez-UrreaGeneral Medicine, Fundación Universitaria San Martín, Medellín, COL.
Andres PuelloInternal Medicine, University of Sucre, Sincelejo, COL.
University of Sucre · COUniversidad de Antioquia · COColombia Adventist University · COSaint Martin University · CO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Anemia is frequently diagnosed in elderly patients, and it is a key indicator of many reactive and clonal conditions. Furthermore, the older age is the most common presenting age for myelodysplastic syndromes (MDS). Anemia in older age may be attributed to an inflammatory state due to senescence, comorbidities, nutritional deficiencies, or primary bone marrow conditions. As diagnostic possibilities and life expectancy increase, the prevalence of anemia of the elderly increases as well. The etiology has a direct impact on the treatment and quality of life of these patients, in whom is a usual clinical challenge as it may be due to a multifactorial origin. In a minority group, when no etiology is identified, it is classified as unexplained anemia (UA) or clonal cytopenia of unknown significance (CCUS). The underlying cause of anemia remains unexplained in 30% of cases, and a great part of unexplained cytopenia may account for myeloid neoplasms. Anemia in the elderly is associated with worse cognitive and functional outcomes and increased mortality.

Indexed as

anemiachronic inflammatory diseasesclonal cytopeniaelderly patientmyelodysplastic syndromes

Identifiers

PMID34984131
PMCPMC8714032
OpenAlexW3214924178

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.