ArticleCureus2021
Prediction of Mucosal Health by NLR, CRP x NLR and MPV in Ulcerative Colitis: Can Their Availability Change According to Treatment Options?
Article in Cureus, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
4 citing papers in PubMed, 1 synthesis or guideline pooled it, 6 citations in OpenAlex.
- The predictive role of peripheral serum inflammatory markers NLR, PLR, and LMR in ulcerative colitis and Crohn's disease: a systematic review and meta-analysis.Frontiers in immunology · 2025Pooled it
- Nutritional Indices as Non-Invasive Biomarkers: PNI and CONUT Scores Predict Clinical and Endoscopic Activity in Ulcerative Colitis.Nutrients · 2026Article
- Leveraging patient-reported outcomes and serum markers to predict active ulcerative colitis: a multicenter cohort.Frontiers in medicine · 2026Article
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Introduction Mucosal healing is the main treatment goal in ulcerative colitis (UC). Many noninvasive parameters have been used in clinical practice to assess mucosal healing. In this study, we aimed to evaluate the effectiveness of neutrophil-lymphocyte ratio (NLR), C-reactive protein (CRP) x NLR and mean platelet volume (MPV) in predicting mucosal health. Method This study was designed as a retrospective and single-center. A total of 165 patients, 126 active and 39 in remission, were included in this study. The patients were divided into two groups. The patients were divided into two groups. Group-1 consisted of newly diagnosed patients and patients using only mesalazine; Group-2 was including patients using CS and/or AZT plus mesalazine for at least one month. The relationship between Rachmilewitz endoscopic activity index (EAI) and erythrocyte sedimentation rate (ESR), CRP, NLR, CRP x NLR, MPV and platelet (PLT) was evaluated. Using receiver operating characteristic curves, cut-off values were determined for these parameters to predict active disease. Results A positive correlation was found between CRP, PLT and NLR and EAI (p<0.001). A negative correlation was found between MPV and EAI (p<0.001). The accuracy of CRP, NLR, CRP x NLR and PLT (2.65 mg/dl, 2.06, 4.29 and 278.5 x 10
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.