Evidence map›Paper›PMID 34984109›Full record

ArticleIEEE journal of translational engineering in health and medicine2022

Evaluation of a Novel Left Ventricular Assist Device for Resuscitation in an Animal Model of Ventricular Fibrillation Cardiac Arrest.

Zongtao Wang, Huiming Yu, Shiping Yan, Hong Yan, Danhong Chen, Yining Dai, Qichun Xu, Zhihuan Zeng, Wei Zhang, Lijun Jin

Open access · goldAbstract read
In one paragraph

Article in IEEE journal of translational engineering in health and medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact, top 84% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Zongtao WangThe First Affiliated Hospital of Guangdong Pharmaceutical University Guangzhou Guangdong 510008 China.ORCID 0000-0002-1481-9936
Huiming YuHypertension Research Laboratory, Guangdong Provincial People's HospitalDepartment of CardiologyGuangdong Cardiovascular Institute, Guangdong Academy of Medical Sciences Guangzhou Guangdong 510080 China.
Shiping YanHunan APT Medical Inc. Xiangxiang 411400 China.
Hong YanHypertension Research Laboratory, Guangdong Provincial People's HospitalDepartment of CardiologyGuangdong Cardiovascular Institute, Guangdong Academy of Medical Sciences Guangzhou Guangdong 510080 China.
Danhong ChenHypertension Research Laboratory, Guangdong Provincial People's HospitalDepartment of CardiologyGuangdong Cardiovascular Institute, Guangdong Academy of Medical Sciences Guangzhou Guangdong 510080 China.
Yining DaiHypertension Research Laboratory, Guangdong Provincial People's HospitalDepartment of CardiologyGuangdong Cardiovascular Institute, Guangdong Academy of Medical Sciences Guangzhou Guangdong 510080 China.
Qichun XuHypertension Research Laboratory, Guangdong Provincial People's HospitalDepartment of CardiologyGuangdong Cardiovascular Institute, Guangdong Academy of Medical Sciences Guangzhou Guangdong 510080 China.
Zhihuan ZengThe First Affiliated Hospital of Guangdong Pharmaceutical University Guangzhou Guangdong 510008 China.ORCID 0000-0002-2701-8556
Wei ZhangThe First Affiliated Hospital of Guangdong Pharmaceutical University Guangzhou Guangdong 510008 China.
Lijun JinHypertension Research Laboratory, Guangdong Provincial People's HospitalDepartment of CardiologyGuangdong Cardiovascular Institute, Guangdong Academy of Medical Sciences Guangzhou Guangdong 510080 China.
Guangdong Academy of Medical Sciences · CNFirst Affiliated Hospital of Guangdong Pharmaceutical University · CNXinxiang Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We evaluated an independently developed novel percutaneous implantable left ventricular assist device for resuscitation in a pig model of ventricular fibrillation cardiac arrest. The model was established in 10 domestic pigs by blocking the anterior descending coronary artery with a balloon after anesthesia. With ventilator-assisted ventilation, the independently developed percutaneous implantable left ventricular assist device was inserted via the femoral artery to assist circulation. According to whether effective circulatory support was achieved, the pigs were randomly divided into an experimental group and a control group. The experimental group was subjected to insertion of the assist device and received continuous circulatory support. The control group underwent insertion of the assist device; however, it did not start it within 15 minutes. For all animals, if successful rescue was achieved (sinus rhythm restoration within 15 minutes and maintenance for over 5 minutes), circulatory support was stopped, and the arterial blockage was removed. If sinus rhythm was not restored within 15 minutes, electric defibrillation, adrenaline injection, and removal of the arterial blockage were performed, and circulatory support was provided until sinus rhythm recovered. A determination of failed rescue was made when sinus rhythm was not restored after 1 hour. All successfully rescued animals were fed for 1 week. There were no significant differences in baseline data between the groups. All animals underwent successful novel left ventricular assist device implantation through the femoral artery. The rescue rate was significantly higher in the experimental group than in the control group (80%

Indexed as

Heart ArrestHeart-Assist DevicesAnimalsDisease Models, AnimalResuscitationSwineVentricular Fibrillationcardiac arrestleft ventricular assist devicePercutaneous implantationrescue

Identifiers

PMID34984109
PMCPMC8719647
OpenAlexW4205110676

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.