Evidence map›Paper›PMID 34984065›Full record

ArticleInterdisciplinary perspectives on infectious diseases2021

Efficacy of Colchicine and Budesonide in Improvement Outcomes of Patients with Coronavirus Infection 2019 in Damascus, Syria: A Randomized Control Trial.

Mohammad Alsultan, Ameer Obeid, Omar Alsamarrai, Mohamed Taher Anan, Aliaa Bakr, Nawwar Soliman, Mamdoh Kurdy, Muhannad Hag Mosa, Zain Saleh, Fatima Hujij and 1 more

Open access · goldAbstract read
In one paragraph

Article in Interdisciplinary perspectives on infectious diseases, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 4 pooled it
0.8field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 4 syntheses or guidelines pooled it, 13 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Inhaled corticosteroids' effect on COVID-19 patients: A systematic review and meta-analysis of randomized controlled trials.Canadian journal of respiratory therapy : CJRT = Revue canadienne de la therapie respiratoire : RCTR · 2023
    Pooled it
  4. Inhaled corticosteroids for the treatment of COVID-19.The Cochrane database of systematic reviews · 2022
    Pooled it
  5. Trial
  6. Trial
  7. Review
  8. Article
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Mohammad AlsultanDepartment of Nephrology, Al Assad and Al Mouwasat University Hospitals, Damascus, Syria.ORCID https://orcid.org/0000-0001-9113-5338
Ameer ObeidDepartment of Infectious Diseases, Al Assad and Al Mouwasat University Hospitals, Damascus, Syria.
Omar AlsamarraiDepartment of Neurology, Al Assad and Al Mouwasat University Hospitals, Damascus, Syria.
Mohamed Taher AnanProfessor, Statics Department, Aleppo University, Aleppo, Syria.
Aliaa BakrDepartment of Oncology, Al Biruni University Hospital, Damascus, Syria.
Nawwar SolimanDepartment of Internal Medicine, Al Assad and Al Mouwasat University Hospitals, Damascus, Syria.
Mamdoh KurdyDepartment of Oncology, Al Biruni University Hospital, Damascus, Syria.
Muhannad Hag MosaDepartment of Internal Medicine, Al Assad and Al Mouwasat University Hospitals, Damascus, Syria.
Zain SalehDepartment of Neurology, Al Assad and Al Mouwasat University Hospitals, Damascus, Syria.
Fatima HujijDepartment of Internal Medicine, Al Assad and Al Mouwasat University Hospitals, Damascus, Syria.
Jafar BarhoumDepartment of Rheumatology, Al Assad and Al Mouwasat University Hospitals, Damascus, Syria.
Al Assad University Hospital · SYUniversity of Aleppo · SY

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

COVID-19 was reported in China in 2019 and has spread worldwide. Transmission occurs through respiratory secretions and, less commonly, through contaminated surfaces. The severity of the disease can range from asymptomatic to acute respiratory distress syndrome (ARDS). In this study, we aim to investigate the efficacy of two agents (oral colchicine and budesonide inhaler) in COVID-19 infection management, compared with supportive care alone. 77 patients were admitted to the isolation section of Al Assad University Hospital, between the 1

Identifiers

PMID34984065
PMCPMC8720363
OpenAlexW4205870397

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.