ReviewJournal of perinatology : official journal of the California Perinatal Association2021
Congenital nephrotic syndrome.
Review in Journal of perinatology : official journal of the California Perinatal Association, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
16 citing papers in PubMed, 34 citations in OpenAlex.
- Positive impact of mobile educational platforms on blood glucose control in patients with nephrotic syndrome and steroid-induced diabetes mellitus: a randomized controlled study.BMC endocrine disorders · 2025Trial
- Combined Fibrinogen and Urinary α1-Microglobulin as Predictors of Respiratory Tract Infection in Children with Nephrotic Syndrome.Medical science monitor : international medical journal of experimental and clinical research · 2026Article
- Promoter Hypermethylation-Driven NPHS2 Silencing Promotes Immune Escape and Sunitinib Resistance in Clear Cell Renal Cell Carcinoma.Oncology research · 2026Article
- Congenital Nephrotic Syndrome in Oman:Sultan Qaboos University medical journal · 2026Article
- Expanded CRB2-related disease phenotype: multisystem involvement and post-transplant complications in monozygotic twins.Pediatric nephrology (Berlin, Germany) · 2025Article
- Novel WT1 and ACTN4 co-mutations in a patient with Denys-Drash syndrome and an atypical, potentially attenuated presentation of nephropathy: a case report.BMC nephrology · 2025Article
- Computational pharmacology-based molecular mechanism investigation of cinnamaldehyde intervention in nephrotic syndrome.Naunyn-Schmiedeberg's archives of pharmacology · 2025Article
- Spontaneous bladder perforation with urinary ascites secondary to posterior urethral valves and suspected atypical congenital nephrotic syndrome of a premature neonate: A case report.Urology case reports · 2025Article
- A novel NPHS1 variant in a Chinese infant with congenital nephrotic syndrome: a case report and literature review.Frontiers in pediatrics · 2025Article
- Advances in Diagnosis and Treatment of Inherited Kidney Diseases in Children.Kidney diseases (Basel, Switzerland) · 2024Review
- Hypogammaglobulinemia in neonates: illustrative cases and review of the literature.Journal of perinatology : official journal of the California Perinatal Association · 2024Review
- Water-soluble vitamins and trace elements in children with chronic kidney disease stage 5d.Pediatric nephrology (Berlin, Germany) · 2024Review
- Nephrotic Syndrome: A Review.Cureus · 2024Review
- Managing venous thrombosis in a pediatric patient with short bowel and congenital nephrotic syndromes: a case report emphasizing rivaroxaban level monitoring.Frontiers in pediatrics · 2024Article
- Effects of a novel ANLN E841K mutation associated with SRNS on podocytes and its mechanism.Cell communication and signaling : CCS · 2023Article
- Usefulness of Early Genetic Diagnosis for Twins With a Family History of Congenital Nephrotic Syndrome.Cureus · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Congenital nephrotic syndrome (CNS), a challenging form of nephrotic syndrome, is characterized by massive proteinuria, hypoalbuminemia, and edema. Extensive leakage of plasma proteins is the main feature of CNS. Patients can be diagnosed in utero or during the first few weeks of life, usually before three months. The etiology of CNS can be related to either genetic or nongenetic etiologies. Pathogenic variants in NPHS1, NPHS2, LAMB2, WT1, and PLCE1 genes have been implicated in this disease. The clinical course is complicated by significant edema, infections, thrombosis, hypothyroidism, failure to thrive, and others. Obtaining vascular access, frequent intravenous albumin infusions, diuretic use, infection prevention, and nutritional support are the mainstay management during their first month of life. The best therapy for these patients is kidney transplantation. CNS diagnosis and treatment continue to be a challenge for clinicians. This review increases the awareness about the pathogenesis, diagnosis, and management of CNS patients.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.