ArticleThe Journal of neuroscience : the official journal of the Society for Neuroscience2022
Distorted Tonotopy Severely Degrades Neural Representations of Connected Speech in Noise following Acoustic Trauma.
Article in The Journal of neuroscience : the official journal of the Society for Neuroscience, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
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Who cites it
21 citing papers in PubMed, 24 citations in OpenAlex.
- Distinct Roles of Working Memory and Inhibitory Control in Speech-in-Noise Perception.bioRxiv : the preprint server for biology · 2026Article
- Comparing physiological signatures of synaptopathic noise exposure and carboplatin-induced inner-hair-cell dysfunction in chinchillas.Hearing research · 2026Article
- Differentiating the Physiological Signatures of Cochlear Synaptopathy and Inner Hair Cell Damage in a Chinchilla Model.bioRxiv : the preprint server for biology · 2026Article
- Feasibility of Ecological Momentary Assessment in the Indian Context to Address Challenges Associated with Hearing-Aid Use.International archives of otorhinolaryngology · 2026Article
- Tonotopic organization in the basal region of the ventromedial nucleus of the thalamus revealed by fiber photometry recording.Neurophotonics · 2026Article
- Effect of digital noise reduction processing on subcortical speech encoding and relationship to behavioral outcomes.Scientific reports · 2025Article
- Evidence for the Auditory Nerve Generating Envelope Following Responses When Measured from Eardrum Electrodes.Journal of the Association for Research in Otolaryngology : JARO · 2025Article
- Sound Advice: A Consumer's Perspective on Navigating the World of Over-the-Counter Hearing Aids.Seminars in hearing · 2025Review
- Speech-in-noise discriminability after noise exposure: Insights from a gerbil model of acoustic trauma.PloS one · 2025Article
- Article
- Impact of reduced spectral resolution on temporal-coherence-based source segregation.The Journal of the Acoustical Society of America · 2024Article
- Effect of digital noise-reduction processing on subcortical speech encoding and relationship to behavioral outcomes.bioRxiv : the preprint server for biology · 2024Article
- Article
- Impact of Reduced Spectral Resolution on Temporal-Coherence-Based Source Segregation.bioRxiv : the preprint server for biology · 2024Article
- Estimation of Cochlear Frequency Selectivity Using a Convolution Model of Forward-Masked Compound Action Potentials.Journal of the Association for Research in Otolaryngology : JARO · 2024Article
- Effect of Cochlear Implant Electrode Insertion Depth on Speech Perception Outcomes: A Systematic Review.Otology & neurotology open · 2023Article
- Cell-type-specific plasticity of inhibitory interneurons in the rehabilitation of auditory cortex after peripheral damage.Nature communications · 2023Article
- Large-scale electrophysiology and deep learning reveal distorted neural signal dynamics after hearing loss.eLife · 2023Article
- Age-Related Hearing Loss, Cognitive Performance, and Metabolic Risk in Healthy Adults: A Seven-Year Longitudinal Study.The journals of gerontology. Series B, Psychological sciences and social sciences · 2023Article
- Altered neural encoding of vowels in noise does not affect behavioral vowel discrimination in gerbils with age-related hearing loss.Frontiers in neuroscience · 2023Article
Corrections and comments
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
Listeners with sensorineural hearing loss (SNHL) struggle to understand speech, especially in noise, despite audibility compensation. These real-world suprathreshold deficits are hypothesized to arise from degraded frequency tuning and reduced temporal-coding precision; however, peripheral neurophysiological studies testing these hypotheses have been largely limited to in-quiet artificial vowels. Here, we measured single auditory-nerve-fiber responses to a connected speech sentence in noise from anesthetized male chinchillas with normal hearing (NH) or noise-induced hearing loss (NIHL). Our results demonstrated that temporal precision was not degraded following acoustic trauma, and furthermore that sharpness of cochlear frequency tuning was not the major factor affecting impaired peripheral coding of connected speech in noise. Rather, the loss of cochlear tonotopy, a hallmark of NH, contributed the most to both consonant-coding and vowel-coding degradations. Because distorted tonotopy varies in degree across etiologies (e.g., noise exposure, age), these results have important implications for understanding and treating individual differences in speech perception for people suffering from SNHL.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.