Evidence map›Paper›PMID 34983690›Full record

ArticleTropical medicine and health2022

The 2017 Dengue virus 1 outbreak in northern Vietnam was caused by a locally circulating virus group.

Taichiro Takemura, Co Thach Nguyen, Ha Chau Pham, Thuy Trang Nguyen, Vu Mai Phuong Hoang, Le Khanh Hang Nguyen, Takeshi Nabeshima, Thi Thu Thuy Nguyen, Thi Quynh Mai Le, Meng Ling Moi and 2 more

Open access · goldAbstract read
In one paragraph

Article in Tropical medicine and health, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
2.6field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 13 citations in OpenAlex.

  1. Article
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  6. Proceedings of the 5th Asia Dengue Summit.Tropical medicine and infectious disease · 2023
    Article
  7. Review
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 2 countries.

Taichiro TakemuraVietnam Research Station, Institute of Tropical Medicine, Nagasaki University, 1-12-4 Sakamoto, Nagasaki-shi, Nagasaki, Japan.
Co Thach NguyenDepartment of Virology, Institute of Tropical Medicine, Nagasaki University, Nagasaki, Japan.
Ha Chau PhamVietnam Research Station, Institute of Tropical Medicine, Nagasaki University, 1-12-4 Sakamoto, Nagasaki-shi, Nagasaki, Japan.
Thuy Trang NguyenVietnam Research Station, Institute of Tropical Medicine, Nagasaki University, 1-12-4 Sakamoto, Nagasaki-shi, Nagasaki, Japan.
Vu Mai Phuong HoangDepartment of Virology, National Institute of Hygiene and Epidemiology, Hanoi, Vietnam.
Le Khanh Hang NguyenDepartment of Virology, National Institute of Hygiene and Epidemiology, Hanoi, Vietnam.
Takeshi NabeshimaVietnam Research Station, Institute of Tropical Medicine, Nagasaki University, 1-12-4 Sakamoto, Nagasaki-shi, Nagasaki, Japan.
Thi Thu Thuy NguyenDepartment of Virology, National Institute of Hygiene and Epidemiology, Hanoi, Vietnam.
Thi Quynh Mai LeDepartment of Virology, National Institute of Hygiene and Epidemiology, Hanoi, Vietnam.
Meng Ling MoiDepartment of Virology, Institute of Tropical Medicine, Nagasaki University, Nagasaki, Japan.
Kouichi MoritaDepartment of Virology, Institute of Tropical Medicine, Nagasaki University, Nagasaki, Japan.
Futoshi HasebeVietnam Research Station, Institute of Tropical Medicine, Nagasaki University, 1-12-4 Sakamoto, Nagasaki-shi, Nagasaki, Japan. rainbow@nagasaki-u.ac.jp.ORCID http://orcid.org/0000-0002-2573-3302
Nagasaki University · JPNational Institute Of Hygiene And Epidemiology · VN

Funding

Japan Agency for Medical Research and Development JP20wm0125006Japan Agency for Medical Research and Development JP21wm0125006
6 · The paper itself

Abstract

backgroundDengue virus (DENV) is a member of insect vector-borne viruses, and it causes dengue fever. Southeast Asia is the epi-center of dengue fever in the world. The characterization of the virus is essential to identify the transmission and evolution of DENV.

objectivesIn 2017, there was an outbreak of Dengue virus type 1 (DENV1) in northern Vietnam and the neighboring countries. To identify the genetic character of the outbreak virus in the area, we conducted whole-genome sequencing analysis on the samples positive for the DENV1 along with real-time PCR. STUDY

designIn total, 1026 blood samples were collected from patients with suspected dengue fever in Ha Nam and Hai Duong province, nearby areas of the capital of Vietnam. After screening by real-time PCR, 40 of DENV1 positive samples were subjected to whole-genome sequencing, and 28 complete coding sequences were obtained.

resultsAll 28 sequences were genotype I of DENV1, which is dominant in the southeast and East Asian countries. The phylogenetic analysis of the E region showed that they fell into a single cluster with the reported sequences from Vietnam between 2009 and 2016, in which the isolates from other countries are very rare. Our results suggested that the 2017 outbreak in the area was caused by locally circulating viruses.

Indexed as

Dengue virusVietnamViral genomeVirus circulation

Identifiers

PMID34983690
PMCPMC8725327
OpenAlexW4206683640

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.