Evidence map›Paper›PMID 34983626›Full record

ArticleCell & bioscience2022

Ontogeny of RORγt

Xiuhao Zhao, Wenhua Liang, Yonghui Wang, Ruirong Yi, Lingjie Luo, Weifang Wang, Nannan Sun, Mingcheng Yu, Weijue Xu, Qingfeng Sheng and 4 more

Open access · goldAbstract read
In one paragraph

Article in Cell & bioscience, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
0.9field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Review
  5. Review
  6. Type 3 immune response protects againstEmerging microbes & infections · 2024
    Article
  7. Review
  8. State-of-the-art review and update ofFrontiers in pediatrics · 2023
    Review
  9. ILC3: a case of conflicted identity.Frontiers in immunology · 2023
    Review
  10. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 2 institutions in 1 country.

Xiuhao Zhao *Department of Gastrointestinal Surgery, Shanghai East Hospital, Tongji University School of Medicine, Shanghai, 200120, China.
Wenhua Liang *Research Center of Translational Medicine, Shanghai Children's Hospital, Shanghai Institute of Immunology, State Key Laboratory of Oncogenes and Related Genes, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Yonghui WangDepartment of Medicinal Chemistry, School of Pharmacy, Fudan University, Shanghai, China.
Ruirong YiResearch Center of Translational Medicine, Shanghai Children's Hospital, Shanghai Institute of Immunology, State Key Laboratory of Oncogenes and Related Genes, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Lingjie LuoResearch Center of Translational Medicine, Shanghai Children's Hospital, Shanghai Institute of Immunology, State Key Laboratory of Oncogenes and Related Genes, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Weifang WangResearch Center of Translational Medicine, Shanghai Children's Hospital, Shanghai Institute of Immunology, State Key Laboratory of Oncogenes and Related Genes, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Nannan SunDepartment of Medicinal Chemistry, School of Pharmacy, Fudan University, Shanghai, China.
Mingcheng YuDepartment of Medicinal Chemistry, School of Pharmacy, Fudan University, Shanghai, China.
Weijue XuDepartment of General Surgery, Shanghai Children's Hospital, Shanghai Jiao Tong University, 355 Luding Road, Putuo, Shanghai, China.
Qingfeng ShengDepartment of General Surgery, Shanghai Children's Hospital, Shanghai Jiao Tong University, 355 Luding Road, Putuo, Shanghai, China.
Li LuDepartment of General Surgery, Shanghai Children's Hospital, Shanghai Jiao Tong University, 355 Luding Road, Putuo, Shanghai, China.
Jianfeng PangResearch Center of Translational Medicine, Shanghai Children's Hospital, Shanghai Institute of Immunology, State Key Laboratory of Oncogenes and Related Genes, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Zhibao LvDepartment of General Surgery, Shanghai Children's Hospital, Shanghai Jiao Tong University, 355 Luding Road, Putuo, Shanghai, China. zhibaolyu@163.com.ORCID http://orcid.org/0000-0002-6854-1394
Feng WangResearch Center of Translational Medicine, Shanghai Children's Hospital, Shanghai Institute of Immunology, State Key Laboratory of Oncogenes and Related Genes, Shanghai Jiao Tong University School of Medicine, Shanghai, China. wangfeng16@sjtu.edu.cn.
Shanghai Jiao Tong University · CNFudan University · CN

Funding

National Key Research and Development Program of China (CN) SQ2018YFA090045-01National Natural Science Foundation of China 81771739National Natural Science Foundation of China 81871194National Natural Science Foundation of China 82071852Top Young Talent Program of Shanghai, and the Technology Committee of Shanghai Municipality 18JC1414100Top Young Talent Program of Shanghai, and the Technology Committee of Shanghai Municipality 18ZR14311300Top Young Talent Program of Shanghai, and the Technology Committee of Shanghai Municipality 20410713800
6 · The paper itself

Abstract

backgroundNeonates possess an immature and plastic immune system, which is a major cause of some diseases in newborns. Necrotizing enterocolitis (NEC) is a severe and devastating intestinal disease that typically affects premature infants. However, the development of intestinal immune cells in neonates and their roles in the pathological process of NEC have not been elucidated.

resultsWe examined the ontogeny of intestinal lamina propria lymphocytes in the early life of mice and found a high percentage of RORγt

conclusionsOur data reveal the high proportion of RORγt

Indexed as

Intestinal immuneNecrotizing enterocolitisNeonateRORγt

Identifiers

PMID34983626
PMCPMC8725364
OpenAlexW4206785285

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.