ArticleParasites & vectors2022
Prospective serological and molecular cross-sectional study focusing on Bartonella and other blood-borne organisms in cats from Catalonia (Spain).
Article in Parasites & vectors, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.
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Who cites it
18 citing papers in PubMed, 1 synthesis or guideline pooled it, 27 citations in OpenAlex.
- A case of mistaken identity: a systematic review, meta-analysis, and reinvestigation of hemotropic Mycoplasma spp. infection in Ctenocephalides felis (cat flea).Parasites & vectors · 2024Pooled it
- Successful Management of Septic Splenitis in an Abyssinian Cat.Veterinary medicine and science · 2026Article
- First PCR-Confirmed Case of Feline Hemoplasmosis in Bosnia and Herzegovina with a Long-Term Follow-Up.Veterinary sciences · 2026Article
- Molecular Detection ofPathogens (Basel, Switzerland) · 2026Article
- Absence of Host-Specific Hemotropic Mycoplasmas in Horses and Donkeys from Croatia: First Systematic Survey in Southeastern Europe.Animals : an open access journal from MDPI · 2026Article
- Prevalence of selected infectious agents in Swedish cats with fever and/or anemia compared to cats without fever and/or anemia and to stable/stray cats.Acta veterinaria Scandinavica · 2025Article
- Prevalence and Risk Factor Analysis of Feline Blood-Borne Pathogens in Bangkok and Vicinities, Thailand.Veterinary medicine international · 2025Article
- Exploring the Zoonotic Risk ofTransboundary and emerging diseases · 2025Article
- Molecular investigation reveals three hemotropic mycoplasmas in cats and three tick species in China.Frontiers in veterinary science · 2025Article
- Feline vector-borne haemopathogens in Türkiye: the first molecular detection of Mycoplasma wenyonii and ongoing Babesia ovis DNA presence in unspecific hosts.BMC veterinary research · 2024Article
- Zoonoses in dog and cat shelters in North-East Italy: update on emerging, neglected and known zoonotic agents.Frontiers in veterinary science · 2024Article
- Molecular survey on vector-borne pathogens in clinically healthy stray cats in Zaragoza (Spain).Parasites & vectors · 2023Article
- Vector-Borne Pathogens in Stray Cats in Eastern Germany (Thuringia).Animals : an open access journal from MDPI · 2023Article
- Article
- ProfilingJournal of veterinary science · 2023Article
- Molecular prevalence and genetic diversity of Bartonella spp. in stray cats of İzmir, Turkey.Parasites & vectors · 2022Article
- Pleural and pericardial effusion associated withJFMS open reportsArticle
- Detection of Bartonella henselae DNA in the blood of patients with livedoid vasculopathy.Anais brasileiros de dermatologiaArticle
Corrections and comments
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Authors and funding
6 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThere is limited clinical or epidemiological knowledge regarding Bartonella infection in cats, and no serological studies have compared the presence of antibodies against different Bartonella species. Moreover, there are limited feline Bartonella studies investigating co-infections with other vector-borne pathogens and the associated risk factors. Therefore, the objective of this study was to investigate Bartonella spp. infections and co-infections with other pathogens in cats from Barcelona (Spain) based on serological and/or molecular techniques and to determine associated risk factors.
methodsWe studied colony and owned cats (n = 135). Sera were tested for Bartonella henselae-, Bartonella quintana-, and Bartonella koehlerae-specific antibodies using endpoint in-house immunofluorescence antibody assays. Bartonella real-time PCR (qPCR) and conventional PCR (cPCR) were performed. In addition, cPCR followed by DNA sequencing was performed for other pathogenic organisms (Anaplasma, Babesia, Cytauxzoon, Ehrlichia, Hepatozoon, hemotropic Mycoplasma, and Theileria spp.).
resultsFrom 135 cats studied, 80.7% were seroreactive against at least one Bartonella species. Bartonella quintana, B. koehlerae, and B. henselae seroreactivity was 67.4, 77.0, and 80.7%, respectively. Substantial to almost perfect serological agreement was found between the three Bartonella species. Colony cats were more likely to be Bartonella spp.-seroreactive than owned cats. Moreover, cats aged ≤ 2 years were more likely to be Bartonella spp.-seroreactive. Bartonella spp. DNA was detected in the blood of 11.9% (n = 16) of cats. Cats were infected with B. henselae (n = 12), B. clarridgeiae (n = 3), and B. koehlerae (n = 1). Mycoplasma spp. DNA was amplified from 14% (n = 19) of cat blood specimens. Cats were infected with Mycoplasma haemofelis (n = 8), Candidatus M. haemominutum (n = 6), Candidatus Mycoplasma turicensis (n = 4), and Mycoplasma wenyonii (n = 1). Anaplasma, Babesia, Cytauxzoon, Ehrlichia spp., Hepatozoon, and Theileria spp. DNA was not amplified from any blood sample. Of the 16 Bartonella spp.-infected cats based on PCR results, six (37%) were co-infected with Mycoplasma spp.
conclusionsBartonella spp. and hemoplasma infections are prevalent in cats from the Barcelona area, whereas infection with Anaplasma spp., Babesia, Cytauxzoon, Ehrlichia spp., Hepatozoon, and Theileria infections were not detected. Co-infection with hemotropic Mycoplasma appears to be common in Bartonella-infected cats. To our knowledge, this study is the first to document M. wenyonii is infection in cats.
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