Evidence map›Paper›PMID 34983482›Full record

Observational studyBMC pulmonary medicine2022

Predictors and outcomes of obstructive sleep apnea in patients with chronic obstructive pulmonary disease in China.

Pan Zhang, Bi Chen, Heqing Lou, Yanan Zhu, Peipei Chen, Zongmei Dong, Xuan Zhu, Ting Li, Peian Lou

Open access · goldAbstract readComparative StudyObservational Study
In one paragraph

Observational study in BMC pulmonary medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 1 pooled it
4.7field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 1 synthesis or guideline pooled it, 42 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Pan Zhang *Department of Control and Prevention of Chronic Non-communicable Diseases of Xuzhou Center for Disease Control and Prevention, 142 West Erhuan Road, Xuzhou, Jiangsu, China.
Bi Chen *Department of Respiratory Medicine, Affiliated Hospital of Xuzhou Medical University, Xuzhou, China.
Heqing LouDepartment of Control and Prevention of Chronic Non-communicable Diseases of Xuzhou Center for Disease Control and Prevention, 142 West Erhuan Road, Xuzhou, Jiangsu, China.
Yanan ZhuDepartment of Respiratory Medicine, Affiliated Hospital of Xuzhou Medical University, Xuzhou, China.
Peipei ChenDepartment of Control and Prevention of Chronic Non-communicable Diseases of Xuzhou Center for Disease Control and Prevention, 142 West Erhuan Road, Xuzhou, Jiangsu, China.
Zongmei DongDepartment of Control and Prevention of Chronic Non-communicable Diseases of Xuzhou Center for Disease Control and Prevention, 142 West Erhuan Road, Xuzhou, Jiangsu, China.
Xuan ZhuDepartment of Control and Prevention of Chronic Non-communicable Diseases of Xuzhou Center for Disease Control and Prevention, 142 West Erhuan Road, Xuzhou, Jiangsu, China.
Ting LiDepartment of Control and Prevention of Chronic Non-communicable Diseases of Xuzhou Center for Disease Control and Prevention, 142 West Erhuan Road, Xuzhou, Jiangsu, China.
Peian LouDepartment of Control and Prevention of Chronic Non-communicable Diseases of Xuzhou Center for Disease Control and Prevention, 142 West Erhuan Road, Xuzhou, Jiangsu, China. lpa82835415@126.com.
Xuzhou Medical College · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

background"Overlap syndrome" refers to obstructive sleep apnea (OSA) combined with chronic obstructive pulmonary disease (COPD), and has poorer outcomes than either condition alone. We aimed to evaluate the prevalence and possible predictors of overlap syndrome and its association with clinical outcomes in patients with COPD.

methodsWe assessed the modified Medical Research Council dyspnea scale (mMRC), Epworth sleepiness scale (ESS), COPD assessment test (CAT), Hospital Anxiety and Depression Scale (HADS), Charlson Comorbidity Index (CCI), and STOP-Bang questionnaire (SBQ) and performed spirometry and full overnight polysomnography in all patients. An apnea-hypopnea index (AHI) ≥ 5 events per hour was considered to indicate OSA. Risk factors for OSA in COPD patients were identified by univariate and multivariate logistic regression analyses.

resultsA total of 556 patients (66%) had an AHI ≥ 5 events per hour. There were no significant differences in age, sex ratio, mMRC score, smoking index, number of acute exacerbations and hospitalizations in the last year, and prevalence of cor pulmonale between the two groups (all p > 0.05). Body mass index (BMI), neck circumference, CAT score, CCI, ESS, HADS, and SBQ scores, forced expiratory volume (FEV)

conclusionPatients with overlap syndrome had a poorer quality of life, more daytime sleepiness, and a higher prevalence of hypertension and diabetes than patients with COPD alone. BMI, neck circumference, ESS, CAT, CCI, HADS, hypertension, and diabetes were independent risk factors for OSA in patients with COPD. The risk of OSA was lower in patients with severe, compared with mild or moderate COPD.

Indexed as

AgedAged, 80 and overChinaCross-Sectional StudiesFemaleHealth Status IndicatorsHumansMaleMiddle AgedPulmonary Disease, Chronic ObstructiveQuality of LifeRisk FactorsSeverity of Illness IndexSleep Apnea, ObstructiveChronic obstructive pulmonary diseaseObstructive sleep apneaPolysomnographyRisk factorScale

Identifiers

PMID34983482
PMCPMC8725359
OpenAlexW4206163305

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.