Evidence map›Paper›PMID 34983468›Full record

ArticleBMC urology2022

Urinary manifestations in African American and Caucasian inflammatory bowel disease patients: a retrospective cohort study.

Jake Herbert, Emily Teeter, Landen Shane Burstiner, Ralfi Doka, Amor Royer, Anna H Owings, Julia Liu, Sarah C Glover, Pegah Hosseini-Carroll

Open access · goldAbstract readComparative Study
PubMed Full text at PMC Publisher
In one paragraph

Article in BMC urology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.9field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 10 citations in OpenAlex.

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  6. Phylogrouping and characterization ofFrontiers in medicine · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 5 institutions in 1 country.

Jake HerbertDr. Kiran C. Patel College of Osteopathic Medicine, Nova Southeastern University, Davie, FL, USA. JH2957@mynsu.nova.edu.
Emily TeeterCollege of Liberal Arts and Sciences, University of Florida, Gainesville, FL, USA.
Landen Shane BurstinerDr. Kiran C. Patel College of Osteopathic Medicine, Nova Southeastern University, Davie, FL, USA.
Ralfi DokaDr. Kiran C. Patel College of Osteopathic Medicine, Nova Southeastern University, Davie, FL, USA.
Amor RoyerDepartment of Internal Medicine, University of Mississippi Medical Center, Jackson, MS, USA.
Anna H OwingsDepartment of Internal Medicine, University of Mississippi Medical Center, Jackson, MS, USA.
Julia LiuDivision of Gastroenterology, Morehouse School of Medicine, Atlanta, GA, USA.
Sarah C GloverDepartment of Digestive Disease, University of Mississippi Medical Center, Jackson, MS, USA.
Pegah Hosseini-CarrollDepartment of Digestive Disease, University of Mississippi Medical Center, Jackson, MS, USA.
Nova Southeastern University · USJackson Memorial Hospital · USUniversity of Mississippi Medical Center · USMorehouse School of Medicine · USUniversity of Florida · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundInflammatory bowel diseases (IBD), like ulcerative colitis (UC) and Crohn's disease (CD), are associated with urinary extra-intestinal manifestations, like urolithiasis and uncomplicated urinary tract infections (UTIs). The literature reviewed for this study identifies an increased association of CD and urolithiasis against the general population as well as UC. Furthermore, the rates in which urinary comorbidities manifest have not been well characterized in cross-race analyses. The purpose of this study is to establish the prevalence of common urinary extra-intestinal manifestations in CD and UC and to further determine at what rate these affect the African American and Caucasian populations. METHODOLOGY: This is a retrospective cohort study using de-identified data collected from a research data base that included 6 integrated facilities associated with one tertiary healthcare center from 2012 to 2019. The electronic chart records for 3104 Caucasian and African American IBD patients were reviewed for frequency of urolithiasis and uncomplicated UTI via diagnosed ICD-10 codes. Comparison between data groups was made using multivariate regressions, t-tests, and chi square tests.

resultsOur study included 3104 patients of which 59% were female, 38% were African American, and 43% were diagnosed with UC. Similar proportions of UC and CD diagnosed patients developed urolithiasis (6.0% vs 6.7%, p = 0.46), as well as uncomplicated UTIs (15.6% vs. 14.9%, p = 0.56). Similar proportions of African American and Caucasian patients developed urolithiasis (5.4% vs 7.0%, p = 0.09), but a higher proportion of African Americans developed uncomplicated UTIs (19.4% vs 12.6%, p ≤ 0.001).

conclusionWe found similar rates of urolithiasis formation in both UC and CD in this study. Furthermore, these rates were not significantly different between African American and Caucasian IBD populations. This suggests that UC patients have an elevated risk of urolithiasis formation as those patients with CD. Additionally, African Americans with IBD have a higher frequency of uncomplicated UTI as compared to their Caucasian counterparts.

Indexed as

Black or African AmericanWhite PeopleAdultAgedCohort StudiesColitis, UlcerativeCrohn DiseaseFemaleHumansMaleMiddle AgedRetrospective StudiesUrologic DiseasesCystitisInflammatory bowel diseaseUrinary tract infectionUrolithiasis

Identifiers

PMID34983468
PMCPMC8728902
OpenAlexW4205333627

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.