Evidence map›Paper›PMID 34983456›Full record

Trial reportBMC pediatrics2022

Adaptation of the INTERGROWTH-21st neurodevelopment assessment (INTER-NDA) to the context of the English-speaking Caribbean.

Randall Waechter, Roberta Evans, Sean Hanna, Toni Murray, Cassandra Mobley, Stephanie Holmes, Rashida Isaac, Rebeca Wolfe, Elbernezer Andrew, Barbara Landon and 1 more

Open access · goldAbstract readRandomized Controlled Trial
In one paragraph

Trial report in BMC pediatrics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 53% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 2 countries.

Randall WaechterSchool of Medicine, St. George's University, True Blue, Grenada, West Indies.ORCID 0000-0002-3872-4245
Roberta EvansThe Windward Islands Research and Education Foundation, True Blue, Grenada, West Indies.ORCID 0000-0002-8310-7721
Sean HannaSchool of Medicine, St. George's University, True Blue, Grenada, West Indies. shanna1@sgu.edu.ORCID 0000-0002-0086-9641
Toni MurrayThe Windward Islands Research and Education Foundation, True Blue, Grenada, West Indies.
Cassandra MobleyThe Windward Islands Research and Education Foundation, True Blue, Grenada, West Indies.
Stephanie HolmesThe Windward Islands Research and Education Foundation, True Blue, Grenada, West Indies.
Rashida IsaacThe Windward Islands Research and Education Foundation, True Blue, Grenada, West Indies.
Rebeca WolfeThe Windward Islands Research and Education Foundation, True Blue, Grenada, West Indies.
Elbernezer AndrewThe Windward Islands Research and Education Foundation, True Blue, Grenada, West Indies.
Barbara LandonThe Windward Islands Research and Education Foundation, True Blue, Grenada, West Indies.
Michelle FernandesNational Institute of Health Research Biomedical Research Centre & Faculty of Medicine, Department of Paediatrics, University of Southampton, Southampton, UK.ORCID 0000-0002-0051-3389
Windward Islands Research and Education Foundation · GDSt. George's University · GDJohn Radcliffe Hospital · GB

Funding

Medical Research Council MR/V029169/1
6 · The paper itself

Abstract

backgroundAdaptation of standardized early child development (ECD) assessments to low- and middle-income countries can be challenging because of culture-specific factors relating to language, content, context, and tool administration, and because the reliance of these tests on specialist healthcare professionals limits their scalability in low resource settings.

methodsWe report the cross-cultural adaptation of an international, standardized ECD instrument, the INTERGROWTH-21st Project Neurodevelopment Assessment (INTER-NDA), measuring cognitive, language, motor and behavioural outcomes in 2-year-olds, from a UK-based English-speaking population to the English-speaking Caribbean. Children aged 22-30 months were recruited from a pre-existing randomized controlled neurodevelopment intervention study in Grenada, West Indies.

resultsEight of 37 INTER-NDA items (22%) were culturally and linguistically adapted for implementation in the Caribbean context. Protocol adherence across seven newly-trained non-specialist child development assessors was 89.9%; six of the seven assessors scored ≥80%. Agreement between the expert assessor and the non-specialist child development assessors was substantial (κ = 0.89 to 1.00 (95% CI [0.58, 1.00]). The inter-rater and test-retest reliability for non-specialist child development assessors was between κ = 0.99 -1.00 (95% CI [0.98, 0.99]) and κ = 0.76 - 1.00 (95% CI [0.33, 1.00]) across all INTER-NDA domains.

conclusionsThe current study provides evidence to support the use of the adapted INTER-NDA by trained, non-specialist assessors to measure ECD prevalence in the English-speaking Caribbean. It also provides a methodological template for the adaptation of child developmental measures to cultural and linguistic contexts that conform to the cultural standards of the countries in which they are utilized to aid in the measurement of neurodevelopmental impairments (NDIs) in a variety of global clinical settings.

Indexed as

Child DevelopmentLanguageChildChild, PreschoolEthnicityHumansInfantReproducibility of ResultsWest IndiesAssessment translationChild assessmentEarly childhood developmentINTER-NDANeurodevelopmental assessment

Identifiers

PMID34983456
PMCPMC8728897
OpenAlexW4220825555

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.