ArticleBMC ophthalmology2022
The effect of longstanding silicone oil on retina choroid and optic nerve in eyes with retinal detachment: an optical coherence tomography study.
Article in BMC ophthalmology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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Who cites it
11 citing papers in PubMed, 12 citations in OpenAlex.
- Unexplained vision loss following silicone oil removal: A systematic review and meta-analysis.Eye (London, England) · 2026Article
- High resolution optical coherence tomography of intraretinal silicone oil migration after repair of fovea sparing retinal detachment.American journal of ophthalmology case reports · 2026Article
- Incidence of and treatment strategies for giant retinal tears in cats with retinal detachment.The Canadian veterinary journal = La revue veterinaire canadienne · 2026Article
- Adhesive bioactive materials in ocular applications: Toward smart, regenerative, and minimally invasive therapies.Bioactive materials · 2026Review
- Successful Removal of Subretinal Silicone Oil Using a Vitreous Fluid Control Kit: A Case Report.Cureus · 2025Article
- Clinical and spectral-domain optical coherence tomography findings and changes in new-onset macular edema after silicone oil tamponade.BMC ophthalmology · 2025Article
- Prognostic Factors for Recurrent Rhegmatogenous Retinal Detachment after Silicone Oil Removal.Korean journal of ophthalmology : KJO · 2024Article
- Use of Dichlorodimethylsilane to Produce Polydimethylsiloxane as a Substitute for Vitreous Humour: Characteristics and In Vitro Toxicity.Journal of functional biomaterials · 2023Article
- Influencing factors of low vision 2 years after vitrectomy for proliferative diabetic retinopathy: an observational study.BMC ophthalmology · 2023Observational
- Subretinal silicone oil: OCT imaging findings and surgical management of a rare and unusual iatrogenic complication of retinal detachment surgery.BMJ case reports · 2023Article
- Subepithelial white deposition in the cornea associated with silicone oil and surgical management: a case report.Frontiers in medicine · 2023Article
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Authors and funding
4 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe study aims to evaluate peripapillary retinal nerve fiber layer thickness (RNFL-T), central macular thickness (MT), choroidal thickness (CT), and thickness of each retinal layer after automatic segmentation in patients who underwent retinal detachment (RD) repair with longstanding silicone oil tamponade.
methodsWe enrolled 33 patients who underwent complicated primary rhegmatogenous RD surgery and followed up with a long-term silicone tamponade were included in this retrospective comparative (case-control) study. RNFL-T, CT, and thickness of each retinal layer after automatic segmentation analysis were measured after the longstanding silicone removal surgery.
resultsThe mean silicone oil removal time was 15.1 ± 15.2 (7-70) months. The overall average thickness of the RNFL was 90.7 ± 13.6 μm in the operated eyes and 118.3 ± 35.6 μm in the sound eyes, with a statistically significant difference. The overall average central MT was 186.3 ± 57.7 μm and was significantly lower in the operated eyes than in the sound eyes. Inner retinal layers of the study group showed a significant thinning in the nerve fiber layer, ganglion cell layer, inner plexiform layer, and inner nuclear layer as compared to that of the sound eyes. The subfoveal CT was 213.7 ± 86.6 μm in the study eyes and 217.7 ± 115.5 μm in the control eyes. There was no significant difference between the study eyes and controls.
conclusionThe effects of silicone oil on the retina remain uncertain; however, morphological results in our study have shown direct or indirect silicone oil-induced toxicity, especially in the inner retinal layers.
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