ArticleBMC infectious diseases2022
Clinical outcomes of dengue virus infection in pregnant and non-pregnant women of reproductive age: a retrospective cohort study from 2016 to 2019 in Paraná, Brazil.
Article in BMC infectious diseases, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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Who cites it
9 citing papers in PubMed, 17 citations in OpenAlex.
- Clinical characteristics and obstetric outcomes of dengue fever in pregnancy: a nationwide population-based study in Taiwan.BMC pregnancy and childbirth · 2026Article
- Pregnant women as a reference population to estimate dengue under-reporting: methodological proposal and application in São Paulo State, Brazil.Revista brasileira de epidemiologia = Brazilian journal of epidemiology · 2026Article
- A Systematic Review and Meta-Analysis of Maternal Dengue Infection and Adverse Pregnancy Outcomes.Cureus · 2025Review
- Sex-specific public health data: analyzing the arboviral impact on women in Brazil.Revista de saude publica · 2025Article
- Impact of Climate Change on Reproductive Health and Pregnancy Outcomes: A Systematic Review.Cureus · 2024Review
- Prevention, diagnosis, and treatment protocol of dengue during pregnancy and the postpartum period.Revista brasileira de ginecologia e obstetricia : revista da Federacao Brasileira das Sociedades de Ginecologia e Obstetricia · 2024Review
- The Innate Immune Response in DENV- and CHIKV-Infected Placentas and the Consequences for the Fetuses: A Minireview.Viruses · 2023Review
- Moderation effects of serotype on dengue severity across pregnancy status in Mexico.BMC infectious diseases · 2023Article
- Perinatal Transmission of Dengue Infection among Dengue Hemorrhagic Fever Outbreaks in Southern Vietnam: The First Case Managed at Tu Du Hospital and Review of Literature.The American journal of tropical medicine and hygiene · 2023Review
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4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe increasing number of dengue cases worldwide implies a greater exposure of at-risk groups, such as pregnant women. DENV infection during pregnancy has been increasingly associated with unfavorable outcomes, but the evolution of the disease and its clinical outcomes remain unclear. The objective of this study was to characterize dengue cases in reproductive aged women by comparing the development of the disease in pregnant and non-pregnant women.
methodsA population based retrospective cohort study that used data reported in the Brazilian Mandatory Notifiable Diseases Information System from 2016 to 2019 in Paraná, Brazil. We compared sociodemographic, clinical, and laboratory variables between pregnant and non-pregnant women. Hospitalization and disease severity classification (Dengue, Dengue with warning signs, Severe Dengue) were considered outcome variables.
resultsThe two groups had differences in the year of notification, age distribution, and region of residence. Laboratory investigation was more frequent among pregnant women, and DENV-2 prevailed in both groups. The risks of hospitalization and development of Severe Dengue were higher in pregnant women. There were no deaths observed among pregnant women.
conclusionThis study identified pregnancy as a risk factor for an increase in the severity of DENV infection. It reinforces the importance of identifying early signs of complication, close monitoring, and adequate treatment for pregnant women.
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