Evidence map›Paper›PMID 34983405›Full record

ArticleBMC infectious diseases2022

Meet-Test-Treat for HCV management: patients' and clinicians' preferences in hospital and drug addiction services in Italy.

Massimo Andreoni, Nicola Coppola, Antonio Craxì, Stefano Fagiuoli, Ivan Gardini, Alessandra Mangia, Felice Alfonso Nava, Patrizio Pasqualetti

Abstract read
In one paragraph

Article in BMC infectious diseases, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Article
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  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Massimo AndreoniInfectious Diseases, Polyclinic of Rome Tor Vergata, Rome, Italy.
Nicola CoppolaInfectious Diseases Unit, Department of Mental Health and Public Medicine, University of Campania Luigi Vanvitelli, Naples, Italy.
Antonio CraxìDepartment of Gastroenterology, University of Palermo, Palermo, Italy.
Stefano FagiuoliGastroenterology Hepatology and Transplantation, ASST Papa Giovanni XXIII, Bergamo, Italy.
Ivan GardiniEpaC Onlus, Italian Liver Patient Association, Monza (MB), Italy.
Alessandra MangiaLiver Unit, Casa Sollievo della Sofferenza Hospital, San Giovanni Rotondo, FG, Italy.
Felice Alfonso NavaPenitentiary Medicine and Drug Abuse Unit, Public Health Service, Padua, Italy.
Patrizio PasqualettiSection of Medical Statistics, Department of Public Health and Infectious Diseases, Sapienza University of Rome, Piazzale Aldo Moro 5, 00185, Rome, Italy. patrizio.pasqualetti@uniroma1.it.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundIt has been estimated that the incidence of chronic hepatitis C virus (HCV) will not decline over the next 10 years despite the improved efficacy of antiviral therapy because most patients remain undiagnosed and/or untreated. This study aimed to investigate the opinion of relevant target populations on the practicability, effectiveness and best modalities of the test-and-treat approach in the fight against HCV in Italy.

methodsA survey was delivered to patients with HCV from the general population, patients from drug addiction services, hospital physicians and healthcare providers for drug addiction services.

resultsFor both hospital clinicians and SerD HCPs, tolerability is shown as the most important feature of a suitable treatment. Time to treatment (the time from first contact to initiation of treatment) is deemed important to the success of the strategy by all actors. While a tolerable treatment was the main characteristic in a preferred care pathway for general patients, subjects from drug addiction services indicated that a complete Meet-Test-Treat pathway is delivered within the habitual care center as a main preference. This is also important for SerD HCPs who are a strong reference for their patients; hospital clinicians were less aware of the importance of the patient-HCP relationship in this process.

conclusionThe health system is bound to implement suitable pathways to facilitate HCV eradication. A Meet-Test-Treat program within the drug addiction services may provide good compliance from subjects mainly concerned with virus transmission.

Indexed as

Hepatitis CHepatitis C, ChronicSubstance-Related DisordersAntiviral AgentsHospitalsHumansIncidenceAntiviral AgentsConjoint analysisHCVHealthcare servicesMeet–Test–TreatPoint of carePreferences

Identifiers

PMID34983405
PMCPMC8725306

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.