Evidence map›Paper›PMID 34983130›Full record

Observational studyInvestigative and clinical urology2022

A novel stricture prevention technique in blunt urethral injury: A multi-center retrospective observational study.

Yang Mi, Jingyu Wang, Jinfeng Wu, Xiaopeng Wang, Bin Yang, Ruimin Ren, Yangang Zhang, Xiaobin Yuan, Xuhui Zhang

Open access · diamondAbstract readMulticenter StudyObservational Study
In one paragraph

Observational study in Investigative and clinical urology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Yang Mi *Department of Urology, Shanxi Bethune Hospital, Shanxi Academy of Medical Sciences, Taiyuan, Shanxi, China.ORCID 0000-0003-3249-5282
Jingyu Wang *Department of Urology, Shanxi Bethune Hospital, Shanxi Academy of Medical Sciences, Taiyuan, Shanxi, China.ORCID 0000-0002-7740-878X
Jinfeng Wu *Department of Urology, Shanxi Bethune Hospital, Shanxi Academy of Medical Sciences, Taiyuan, Shanxi, China.ORCID 0000-0002-5193-7683
Xiaopeng WangDepartment of Anesthesiology, Shanxi Bethune Hospital, Shanxi Academy of Medical Sciences, Taiyuan, Shanxi, China.ORCID 0000-0003-1343-5823
Bin YangDepartment of Urology, Shanxi Bethune Hospital, Shanxi Academy of Medical Sciences, Taiyuan, Shanxi, China.ORCID 0000-0001-7628-5303
Ruimin RenDepartment of Urology, Shanxi Bethune Hospital, Shanxi Academy of Medical Sciences, Taiyuan, Shanxi, China.ORCID 0000-0002-7062-368X
Yangang ZhangDepartment of Urology, Shanxi Bethune Hospital, Shanxi Academy of Medical Sciences, Taiyuan, Shanxi, China.ORCID 0000-0002-6317-3166
Xiaobin YuanDepartment of Urology, First Hospital of Shanxi Medical University, Taiyuan, Shanxi, China.ORCID 0000-0002-0497-430X
Xuhui ZhangDepartment of Urology, First Hospital of Shanxi Medical University, Taiyuan, Shanxi, China. zhangxuhui7576@163.com.ORCID 0000-0003-3202-1159
Shanxi Academy of Medical Sciences · CNShanxi Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeBulbar injury is the most common type of urethral injury. This study investigated the efficacy and safety of a novel technique, local urethral flushing, in preventing stricture formation after blunt bulbar urethra injuries. MATERIALS AND

methodsThis retrospective study included 205 males diagnosed with straddle injury-induced bulbar urethra injury at the Shanxi Bethune Hospital and First Hospital of Shanxi Medical University between January 2015 and January 2019. Patients were diagnosed by retrograde urethrography and classified as partial or complete urethral rupture according to the urethral integrity after injury. Complete urethral rupture patients received suprapubic cystostomy and received urethroplasty 3 months later. Patients with partial urethral rupture underwent endoscopic urethral realignment by cystoscopic guide-wire guided catheterization. Patients with both injury types were divided into 3 groups. The treatment groups received urethral flushing with 0.05% dexamethasone through a secondary ureteral catheter that locked at the urethral lesion. The blank control groups received normal saline. The negative control groups had only a single ureteral catheter placed. Patients were assessed for pain during catheterization, infection, and stenosis, and followed for at least 2 years.

resultsStenosis rates and length were significantly reduced in the normal saline groups, and even further reduced in the dexamethasone groups. The negative control groups had significantly higher infection rates than patients in the dexamethasone or saline groups.

conclusionsLocal urethral flushing with dexamethasone could significantly decrease urethral stenosis rates and severity without increasing patients' discomfort or infection risk.

Indexed as

AdultHumansMaleMiddle AgedRetrospective StudiesTherapeutic IrrigationTreatment OutcomeUrethraUrethral StrictureWounds, NonpenetratingBlunt injuryBulbar urethraDexamethasoneLocal urethral flushing

Identifiers

PMID34983130
PMCPMC8756155
OpenAlexW4226036015

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.