ArticleInvestigative and clinical urology2022
Evaluating the efficacy of secondary transurethral resection of the bladder for high-grade Ta tumors.
Article in Investigative and clinical urology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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Who cites it
7 citing papers in PubMed, 9 citations in OpenAlex.
- Reassessing re-TURBT in the modern era: Is it time to move from routine to selective?BJUI compass · 2026Article
- Therapeutic and prognostic value of repeat transurethral resection for high-grade Ta bladder cancer: a propensity score matching analysis.American journal of cancer research · 2026Article
- Is a second TUR necessary in patients with primary high-grade Ta NMIBC, particularly in the context of initial cases?BJUI compass · 2025Article
- Utility of restaging transurethral resection in patients with primary high-grade Ta bladder cancer.World journal of urology · 2025Article
- Intravesical chemotherapy in BCG waiting period may prolong time to recurrence for high-risk NMIBC patients.BMC cancer · 2025Article
- IVC treatment between primary and second TURBT may improve the prognosis of high-risk NMIBC patients receiving BCG treatment.Scientific reports · 2025Article
- Repeat TURBT in large volume high-grade non-invasive bladder cancer.Bladder cancer (Amsterdam, Netherlands) · 2024Article
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeThe need for secondary transurethral resection of the bladder (re-TURB) in patients with high-grade Ta tumors has not been assessed. This study aimed to compare the outcomes of patients with high-grade Ta tumors who did and did not undergo re-TURB. MATERIALS AND
methodsThis study used data from the Seoul National University Prospectively Enrolled Registry for Urothelial Cancer-Transurethral Bladder Tumor Resection (SUPER-UC-TURB). Patients with high-grade Ta tumors who underwent TURB between March 2016 and December 2019 were included. Following the initial TURB, if the pathology results showed a tumor grade higher than high-grade Ta, re-TURB was performed according to the surgeon's recommendation. The recurrence-free survival rate was assessed by Kaplan-Meier analysis and Cox regression analysis between patients who did and did not undergo re-TURB.
resultsIn total, 187 patients with high-grade Ta who underwent initial TURB were included, of whom 115 underwent re-TURB and 72 did not. Patients in the re-TURB group had a significantly higher 2-year recurrence-free survival rate than did those in the no re-TURB group (81.3% vs. 60.1%; p=0.005). Whether patients underwent re-TURB was a significant predictor of the risk of bladder cancer recurrence in both the univariate (HR, 0.52; 95% CI, 0.27-0.98; p=0.044) and multivariate (HR, 0.41; 95% CI, 0.19-0.97; p=0.041) analysis.
conclusionsThe risk for bladder cancer recurrence was increased, and the 2-year recurrence-free survival was significantly decreased, in patients with high-grade Ta tumors who did not undergo re-TURB. Thus, re-TURB is beneficial in patients with high-grade Ta bladder cancer.
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