Evidence map›Paper›PMID 34983113›Full record

ArticleAllergy, asthma & immunology research2022

IgE and IgG Anti-Thyroid Autoantibodies in Chinese Patients With Chronic Spontaneous Urticaria and a Literature Review.

Liming Zhang, Li Qiu, Jian Wu, Yumeng Qi, Hexiao Wang, Ruiqun Qi, Xu Yao, Hong Zhu, Yuzhen Li, Siyu Hao and 32 more

Open access · diamondAbstract read
In one paragraph

Article in Allergy, asthma & immunology research, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
2.9field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 20 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Autoallergy and what the Allergist Needs to know.Current allergy and asthma reports · 2025
    Review
  5. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

42 authors at 15 institutions in 1 country.

Liming ZhangDepartment of Dermatology, The First Hospital of China Medical University, National Health Commission Key Laboratory of Immunodermatology, Key Laboratory of Immunodermatology of Ministry of Education, Shenyang, China.ORCID https://orcid.org/0000-0002-9693-1082
Li QiuDepartment of Dermatology, The First Hospital of China Medical University, National Health Commission Key Laboratory of Immunodermatology, Key Laboratory of Immunodermatology of Ministry of Education, Shenyang, China.ORCID https://orcid.org/0000-0003-0209-9449
Jian WuDepartment of Dermatology, The First Hospital of China Medical University, National Health Commission Key Laboratory of Immunodermatology, Key Laboratory of Immunodermatology of Ministry of Education, Shenyang, China.ORCID https://orcid.org/0000-0001-5238-7479
Yumeng QiDepartment of Dermatology, The First Hospital of China Medical University, National Health Commission Key Laboratory of Immunodermatology, Key Laboratory of Immunodermatology of Ministry of Education, Shenyang, China.ORCID https://orcid.org/0000-0003-2202-3812
Hexiao WangDepartment of Dermatology, The First Hospital of China Medical University, National Health Commission Key Laboratory of Immunodermatology, Key Laboratory of Immunodermatology of Ministry of Education, Shenyang, China.ORCID https://orcid.org/0000-0001-6669-818X
Ruiqun QiDepartment of Dermatology, The First Hospital of China Medical University, National Health Commission Key Laboratory of Immunodermatology, Key Laboratory of Immunodermatology of Ministry of Education, Shenyang, China.ORCID https://orcid.org/0000-0002-5856-4584
Xu YaoDepartment of Allergy and Rheumatology, Hospital for Skin Diseases, Institute of Dermatology, Chinese Academy of Medical Sciences and Peking Union Medical College, Nanjing, China.ORCID https://orcid.org/0000-0003-3509-4775
Hong ZhuDepartment of Allergy and Rheumatology, Hospital for Skin Diseases, Institute of Dermatology, Chinese Academy of Medical Sciences and Peking Union Medical College, Nanjing, China.
Yuzhen LiDepartment of Dermatology, The Second Affiliated Hospital of Harbin Medical University, Harbin, China.ORCID https://orcid.org/0000-0002-3362-5459
Siyu HaoDepartment of Dermatology, The Second Affiliated Hospital of Harbin Medical University, Harbin, China.ORCID https://orcid.org/0000-0002-9624-3642
Qianjin LuDepartment of Dermatology, The Second Xiangya Hospital of Central South University, Changsha, China.ORCID https://orcid.org/0000-0002-7749-9618
Hai LongDepartment of Dermatology, The Second Xiangya Hospital of Central South University, Changsha, China.ORCID https://orcid.org/0000-0001-6135-1486
Shi LianDepartment of Dermatology, Xuan Wu Hospital Capital Medical Univerisity, Beijing, China.ORCID https://orcid.org/0000-0002-0054-7650
Haiping ZhangDepartment of Dermatology, Xuan Wu Hospital Capital Medical Univerisity, Beijing, China.ORCID https://orcid.org/0000-0002-1390-643X
Wei ZhuDepartment of Dermatology, Xuan Wu Hospital Capital Medical Univerisity, Beijing, China.ORCID https://orcid.org/0000-0001-6550-593X
Wei LaiDepartment of Dermatology, The Third Affiliated Hospital of Sun Yat-sen University, Guangzhou, China.ORCID https://orcid.org/0000-0002-2784-492X
Xiangyang SuDepartment of Dermatology, The Third Affiliated Hospital of Sun Yat-sen University, Guangzhou, China.ORCID https://orcid.org/0000-0003-1237-7342
Rongbiao LuDepartment of Dermatology, The Third Affiliated Hospital of Sun Yat-sen University, Guangzhou, China.ORCID https://orcid.org/0000-0001-8609-2361
Zaipei GuoDepartment of Dermatology, West China Hospital, Sichuan University, Chengdu, China.ORCID https://orcid.org/0000-0001-6671-8304
Jingyi LiDepartment of Dermatology, West China Hospital, Sichuan University, Chengdu, China.ORCID https://orcid.org/0000-0003-1320-366X
Mengmeng LiDepartment of Dermatology, West China Hospital, Sichuan University, Chengdu, China.ORCID https://orcid.org/0000-0003-3967-8372
Quanzhong LiuDepartment of Dermatology, Tianjin Medical University General Hospital, Tianjin, China.ORCID https://orcid.org/0000-0002-2318-6261
Huiping WangDepartment of Dermatology, Tianjin Medical University General Hospital, Tianjin, China.ORCID https://orcid.org/0000-0002-0385-4701
Li HeDepartment of Dermatology, First Affiliated Hospital of Kunming Medical University, Kunming, China.
Xiang NongDepartment of Dermatology, First Affiliated Hospital of Kunming Medical University, Kunming, China.ORCID https://orcid.org/0000-0002-0856-6063
Fuqiu LiDepartment of Dermatology, The Second Hospital of Jilin University, Changchun, China.ORCID https://orcid.org/0000-0002-2175-5782
Yang LiDepartment of Dermatology, The Second Hospital of Jilin University, Changchun, China.
Chunli YaoDepartment of Dermatology, The Second Hospital of Jilin University, Changchun, China.ORCID https://orcid.org/0000-0002-8251-1810
Jinhua XuDepartment of Dermatology, Huashan Hospital, Fudan Univeristy, Shanghai, China.ORCID https://orcid.org/0000-0001-9104-1294
Hui TangDepartment of Dermatology, Huashan Hospital, Fudan Univeristy, Shanghai, China.ORCID https://orcid.org/0000-0002-8525-9147
Duoqin WangDepartment of Dermatology, Huashan Hospital, Fudan Univeristy, Shanghai, China.ORCID https://orcid.org/0000-0001-9395-5401
Zhenlu LiDepartment of Dermatology, Henan Provincial People's Hospital, Zhengzhou, China.ORCID https://orcid.org/0000-0002-3273-0222
Huiqian YuDepartment of Dermatology, Henan Provincial People's Hospital, Zhengzhou, China.ORCID https://orcid.org/0000-0003-0734-3332
Shengxiang XiaoDepartment of Dermatology, The Second Affiliated Hospital, School of Medicine, Xi'an Jiaotong University, Xi'an, China.ORCID https://orcid.org/0000-0002-3863-1065
Jingang AnDepartment of Dermatology, The Second Affiliated Hospital, School of Medicine, Xi'an Jiaotong University, Xi'an, China.ORCID https://orcid.org/0000-0002-9614-0280
Xiongming PuDepartment of Dermatology, People's Hospital of Xinjiang Uygur Autonomous Region, Xinjiang Key Laboratory of Dermatology Research (XJYS1707), Urumqi, China.ORCID https://orcid.org/0000-0001-5426-5600
Shirong YuDepartment of Dermatology, People's Hospital of Xinjiang Uygur Autonomous Region, Xinjiang Key Laboratory of Dermatology Research (XJYS1707), Urumqi, China.ORCID https://orcid.org/0000-0002-0884-9987
Jianzhong ZhangDepartment of Dermatology, Peking University People's Hospital, Beijing, China.ORCID https://orcid.org/0000-0002-5485-682X
Xue ChenDepartment of Dermatology, Peking University People's Hospital, Beijing, China.ORCID https://orcid.org/0000-0002-7443-1335
Xinghua GaoDepartment of Dermatology, The First Hospital of China Medical University, National Health Commission Key Laboratory of Immunodermatology, Key Laboratory of Immunodermatology of Ministry of Education, Shenyang, China.ORCID https://orcid.org/0000-0001-8809-8564
Hongduo ChenDepartment of Dermatology, The First Hospital of China Medical University, National Health Commission Key Laboratory of Immunodermatology, Key Laboratory of Immunodermatology of Ministry of Education, Shenyang, China. hongduochen@hotmail.com.ORCID https://orcid.org/0000-0003-1556-1575
Ting XiaoDepartment of Dermatology, The First Hospital of China Medical University, National Health Commission Key Laboratory of Immunodermatology, Key Laboratory of Immunodermatology of Ministry of Education, Shenyang, China. cmuxt@126.com.ORCID https://orcid.org/0000-0003-4107-0454
First Hospital of China Medical University · CNHarbin Medical University · CNHuashan Hospital · CNSichuan University · CNSun Yat-sen University · CNTianjin Medical University General Hospital · CNXuan Wu Hospital of the Capital Medical University · CNCentral South University · CNChinese Academy of Medical Sciences & Peking Union Medical College · CNHenan Provincial People's Hospital · CNKunming Medical University · CNPeking University · CNPeople's Hospital of Xinjiang Uygur Autonomous Region · CNSecond Affiliated Hospital of Jilin University · CNSecond Affiliated Hospital of Xi'an Jiaotong University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Immunoglobulin (Ig) E and IgG anti-thyroid autoantibodies (AAbs) play important roles in the immunopathogenesis of chronic spontaneous urticaria (CSU). To date, association of IgE and IgG AAbs with Chinese CSU patients has not been fully investigated. We aimed to explore prevalence rates of IgE and IgG AAbs in Chinese CSU patients and their association with clinical and laboratory parameters. Serum IgE and IgG AAbs against thyroid peroxidase (TPO) and thyroglobulin (TG), total IgE (tIgE) and specific IgEs were measured using enzyme-linked immunosorbent assay, chemiluminescence microparticle immunoassay and immunoblotting. Meta-analyses and literature review were conducted. The meta-analyses indicated that CSU cases were 4.98, 6.90 and 6.68 times more likely to have positive anti-TPO IgE, anti-TPO IgG and anti-TG IgG (all

Indexed as

Chronic spontaneous urticariaimmunoglobulin Ethyroglobulinthyroid peroxidase

Identifiers

PMID34983113
PMCPMC8724827
OpenAlexW4205558032

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.